research Alopecia - the search for novel agents continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
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research Redefining hormone resistance in prostate cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Polycystic ovary syndrome [PCOS]: Comprehensive management in primary care
Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
research The clinical evaluation of hirsutism
Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.
research Antiandrogen therapy in hidradenitis suppurativa: finasteride for females
Finasteride helps reduce hidradenitis suppurativa symptoms in females.
research Hemodynamic effects of minoxidil following intravenous infusions in untreated hypertensive patients.
Minoxidil given intravenously caused small changes in diastolic blood pressure and increased heart rate at higher concentrations in patients with high blood pressure.
research What every physician should know about polycystic ovary syndrome
Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.
research Low-level light therapy and hair loss
Low-level light therapy is FDA-approved for male pattern hair loss, increases hair count and strength, and is considered safe for use.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research Antiandrogenic therapy with ciproterone acetate in female patients who suffer from both androgenetic alopecia and acne vulgaris
Ciproterone acetate improves hair regrowth and acne in most female patients.
research Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
research Nonsurgical Therapy for Hair Loss
Some nonsurgical hair loss treatments are effective, especially if started early.
research Metformin or thiazolidinedione therapy in PCOS?
Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
research Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study
Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
research Diagnostic applications and therapeutic option of Cascade CRISPR/Cas in the modulation of miRNA in diverse cancers: promises and obstacles
CRISPR/Cas systems show promise for cancer treatment by targeting miRNAs, but delivery and specificity challenges remain.
research Additive in vivo growth-inhibitory effects of flutamide and finasteride on androgen-sensitive Shionogi 115 carcinoma
Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
research Efficacy of Fire Needle Therapy Combined with Doxycycline Hydrochloride in the Management of Moderate-to-Severe Acne Vulgaris: A Randomized Controlled Trial
Combining fire needle therapy with doxycycline improves severe acne more than doxycycline alone.
research Androgenetic Alopecia: Therapy Update
There are many treatments for common hair loss, but more trials are needed to decide which are best.
research Therapeutic Approach to Androgenetic Alopecia
Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
research Systematic review of low-level laser therapy for adult androgenic alopecia
Low-level laser therapy can stimulate hair growth more effectively than fake devices, but patient satisfaction is similar for both. Results should be taken with caution due to small study sizes and differences between studies. More research is needed.
research Low fluence-high repetition rate diode laser hair removal 12-month evaluation: Reducing pain and risks while keeping clinical efficacy
A low-power, fast laser safely reduces hair with minimal pain and few side effects.
research Cross-sex hormone therapy for gender dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Cross-sex hormone therapy in Australia: the prescription patterns of clinicians experienced in adult transgender healthcare
Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study
Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.
research Platelet-rich Plasma and Cell Therapy
PRP and cell therapies may help with hair loss, but more research is needed.
research The Safety of Testosterone Therapy in Women
Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.