101 citations
,
November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
100 citations
,
March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
27 citations
,
August 1984 in “Experimental and Molecular Pathology”
25 citations
,
December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.
24 citations
,
January 1993 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, works better for women, and requires consistent use.
24 citations
,
February 1987 in “Drugs” Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.
18 citations
,
March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
10 citations
,
May 2020 in “Journal of Dermatological Treatment” Microneedling with 5% minoxidil improves hair loss in Chinese men by activating Wnt/ß-catenin pathway.
8 citations
,
October 2018 in “Dermatologic Therapy” About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.
5 citations
,
January 2018 in “Javma-journal of The American Veterinary Medical Association” A dog fully recovered from minoxidil poisoning after receiving treatment.
5 citations
,
March 2016 in “Acute medicine & surgery” Swallowing a lot of minoxidil, a hair growth liquid, can cause severe and long-lasting low blood pressure.
397 citations
,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
219 citations
,
March 2004 in “Journal of The American Academy of Dermatology” 5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
102 citations
,
September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
75 citations
,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
57 citations
,
August 2003 in “British Journal of Dermatology” Minoxidil and pyrithione zinc combo most effectively increases hair density.
41 citations
,
January 2007 in “Journal of Korean Medical Science” Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
38 citations
,
June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
38 citations
,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
34 citations
,
January 1987 in “Dermatology” Topical minoxidil effectively and safely treats extensive alopecia areata but doesn't change its course.
33 citations
,
October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
27 citations
,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
25 citations
,
January 2010 in “International Journal of Pharmaceutics” Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
23 citations
,
June 2017 in “Rejuvenation Research” Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.
21 citations
,
January 2017 in “Skin Pharmacology and Physiology” Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.
18 citations
,
October 2005 in “International Journal of Pharmaceutics” Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.
17 citations
,
June 2019 in “Cellular signalling” Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
17 citations
,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
15 citations
,
November 2019 in “Cutaneous and Ocular Toxicology” Minoxidil tretinoin liposomal based hydrogel shows promise for effective treatment of hair loss by delivering both drugs at the same time.
15 citations
,
May 2017 in “Journal of Dermatological Treatment” Latanoprost works better for hair growth, and combining it with betamethasone valerate is most effective.