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Merkel cell carcinoma is most likely to recur within two years of diagnosis, and factors like immune suppression, being over 75, and male sex increase this risk.

The Hedgehog signaling pathway is linked to cancer development, and targeting it with inhibitors shows promise but faces challenges like resistance.

Hair follicles supply a crucial brain development protein to the brain via platelets.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Phospholipids help plant proteins move by regulating receptor interactions.

Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Lhx2 helps retinal cells respond to signals for eye development.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

LHX2 is crucial for development, tissue repair, and preventing diseases.

Sonic hedgehog signaling helps heal pressure ulcers by improving blood vessel growth.

Sonic hedgehog signaling is crucial for normal wound healing.

Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.

The ubiquitin-mediated proteolysis pathway is crucial for hair follicle development in cashmere goats.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Pigs are a good model for studying human hair growth and disorders.

The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.

Hair growth and development are controlled by specific signaling pathways.

Hair growth and development are controlled by complex signaling pathways.

mTOR may link different pathways in hair follicle tumor formation.

Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

Targeting NMMHC IIA may help treat blood-brain barrier damage.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Equine hoof progenitor cells can help develop therapies for hoof diseases like laminitis.

Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Hedgehog signaling is crucial for mammary gland development over hair follicles.