5 citations
,
September 2015 in “PubMed” Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
4 citations
,
August 2022 in “International Journal of Molecular Sciences” Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
4 citations
,
July 2020 in “Journal of proteomics” Hair protein composition is similar across different races and shapes.
4 citations
,
August 2018 in “Journal of cellular biochemistry” Acid inside cells speeds up aging and turns on aging signs in mice.
3 citations
,
July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
2 citations
,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
2 citations
,
January 2015 in “Elsevier eBooks” Epigenetic changes contribute to autoimmune skin diseases.
1 citations
,
July 2021 in “Health & Medical Journal” Men with systemic lupus erythematosus often have more severe symptoms but can respond well to treatment.
1 citations
,
August 2025 in “Epigenetics & Chromatin” H3K4me3 helps control RSPO3 to influence hair growth and development.
1 citations
,
January 2023 in “Pharmacophore” Tea compound EGCG may slow aging by affecting gene activity.
March 2026 in “Frontiers in Cell and Developmental Biology” Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.
February 2026 in “Advanced Science” Targeting the p300/AR axis may help treat polycystic ovary syndrome.
November 2025 in “Journal of Investigative Dermatology” CBD can help hair grow by supporting scalp health and reducing inflammation.
January 2025 in “Stem Cells International” Epigenetic changes in skin cells contribute to aging, but targeting these changes may offer new antiaging treatments.
February 2024 in “Epigenomes” Epigenetic mechanisms control skin development by regulating gene expression.
Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
April 2023 in “Journal of Investigative Dermatology” LSD1 is essential for healthy skin development and creating the skin's protective barrier.
Low-dose radiation and certain drugs can inhibit keloid growth, revealing potential treatment targets.
September 2017 in “Journal of Investigative Dermatology” Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
Both changes in genes and environmental factors like diet and toxins can significantly affect the growth of skin appendages like hair, but how these factors interact is still unclear.
August 2013 in “eCommons (Cornell University)” Runx1 and CDK inhibitors help keep hair follicle stem cells inactive, affecting their future roles.
August 2012 in “Nature Cell Biology” Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.
April 2012 in “Encyclopedia of Life Sciences” Different genes are linked to various types of hair loss.
Mutations in the hairless protein gene cause hair loss.
1 citations
,
January 2006 in “Clínicas obstétricas y ginecológicas de Norteamérica” Analyzing hair proteins can help identify new markers for hair health and aging.
38 citations
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April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
7 citations
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March 2018 in “Experimental Dermatology” Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.
4 citations
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September 2020 in “Cell division” XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists found new and known long non-coding RNAs in mouse hair follicle stem cells that may be important for stem cell function and could be targets for cancer treatment.