April 2023 in “JMIR Research Protocols” The study aims to create a model to predict health attributes using diverse health data from Japanese adults.
September 2019 in “Journal of Investigative Dermatology” The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.
1 citations
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July 2025 in “Methods and Protocols” The CAM is a useful model for studying burn wounds and testing treatments.
110 citations
,
August 2011 in “Journal of Visualized Experiments” 3D skin models better mimic human skin and melanoma progression than older methods.
130 citations
,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
The study aims to create a model to improve personalized and preventive health care.
September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
4 citations
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June 2021 in “Dermatology” Scientists created a 3D skin model to study a chronic skin disease and test treatments.
15 citations
,
December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The study developed a 3D model that closely imitates remaining ovarian cancer after treatment and identified a potential drug targeting resistant cancer cells.
8 citations
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October 2022 in “International Journal of Molecular Sciences” The hydrogels improved healing in deep second-degree burns.
March 2026 in “Balkan Sağlık Bilimleri Dergisi” Hemşire navigatör modeli, PKOS'lu kadınların tedaviye uyumunu ve yaşam kalitesini artırır.
January 2002 in “Europe PMC (PubMed Central)” The model successfully simulates human hair growth and patterns, including hair loss types.
35 citations
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October 2014 in “Wound Repair and Regeneration” The model helps understand scar contraction and develop new treatments.
September 2022 in “PubMed” Personalized homeopathy medicine, along with lifestyle changes, can effectively treat Polycystic Ovarian Syndrome.
September 2023 in “Reports of Vinnytsia National Medical University” The models accurately predicted urticaria in Ukrainian women but struggled to differentiate between mild and severe cases based on body structure.
11 citations
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January 2022 in “Methods in cell biology” 
47 citations
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November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
July 2025 in “Journal of Cosmetic Dermatology” The model shows how heat damages hair, helping test hair care products.
24 citations
,
September 2018 in “Journal of Materials Science: Materials in Medicine” Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
9 citations
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July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
67 citations
,
July 2000 in “Proceedings of the National Academy of Sciences” The model accurately simulates human hair growth and hair loss patterns.
66 citations
,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicles repair 3D injuries using a 2D healing process.
2 citations
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February 2025 in “Advanced Healthcare Materials” Perhexiline can effectively target ovarian cancer cells left after treatment.
May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids (HFOs) are emerging as valuable in vitro models that mimic the structure and function of native hair follicles, offering new insights into hair biology and disorders. This review discusses the construction of HFOs, emphasizing the importance of epithelial–mesenchymal interactions and comparing various generation strategies, such as primary cell-based co-culture systems and iPSC-derived methods. HFOs have applications in disease modeling, drug screening, and regenerative medicine, but face challenges like large-scale cultivation and standardization. Future advancements in biomaterials and bioengineering are anticipated to improve their physiological relevance and clinical translation potential.
The model explains how mammal ear hair cells respond to sound and adapt.
4 citations
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August 2019 in “Journal of Dermatology” The conclusion is that balancing cost and carbon emissions in hybrid power systems is crucial, especially when high reliability is needed, but the model needs to consider all device efficiencies and distribution losses.
December 2025 in “Advanced Healthcare Materials” The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
20 citations
,
May 2011 in “Journal of Clinical Investigation” The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.