research Features of hemorheological disorders in patients with alopecia associated with coronavirus infection
COVID-19-related hair loss may be linked to blood flow disorders and inflammation.
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research Double Network Physical Crosslinked Hydrogel for Healing Skin Wounds: New Formulation Based on Polysaccharides and Zn2+
The new hydrogel with zinc and polysaccharides improves wound healing and has antibacterial properties.
research Beyond Wavy Hairs
EGFR signaling is crucial for skin and hair health, and targeting it could help treat skin diseases and cancer.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Cannabinoids may help treat various skin conditions.
research The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
3D skin models better mimic human skin and melanoma progression than older methods.
research Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth
Blimp1 is crucial for hair follicle growth and skin health.
research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes
Hairless protein can block vitamin D activation in skin cells.
research FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
research Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication
Laminin α5 is essential for skin communication and health.
research Immune-Epithelial Cross Talk in Regeneration and Repair
Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
research The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris
Psoriasis involves an imbalance between certain immune cells, and targeting these could help restore skin health.
research C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
research Macrophage ferroportin is essential for stromal cell proliferation in wound healing
Macrophage iron release is crucial for hair growth and wound healing.
research Mechanisms Involved in the Relationship between Vitamin D and Insulin Resistance: Impact on Clinical Practice
Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
research Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death
Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
research A systematic summary of survival and death signalling during the life of hair follicle stem cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research The Mixed Lineage Kinase Leucine-Zipper Protein Kinase Exhibits a Differentiation-Associated Localization in Normal Human Skin and Induces Keratinocyte Differentiation upon Overexpression
ZPK helps skin cells mature and may affect skin health.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research Eavesdropping on the conversation between immune cells and the skin epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
research CFTR potentiator ivacaftor protects against noise-induced hair cell loss by increasing Nrf2 and reducing oxidative stress
Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
research A Review of the Impact of Calorie Restriction on Stem Cell Potency
Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.
research The Physiological Impact of Melatonin, Its Effect on the Course of Diseases and Their Therapy and the Effect of Magnetic Fields on Melatonin Secretion—Potential Common Pathways of Influence
Melatonin may help treat various diseases and is influenced by magnetic fields, but more research is needed.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research The expanding impact of T-regs in the skin
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture
Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
research Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing
The zinc-coordinated nanogel therapy speeds up wound healing after pancreas surgery by balancing metabolism and fighting bacteria.
research Alopecia Areata and Atopic Dermatitis: Common Mechanisms and Emerging Therapeutics
Alopecia areata and atopic dermatitis share immune system issues, and treatments like JAK inhibitors can help both.