24 citations
,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
18 citations
,
July 2012 in “Cell Biology International Reports” Human mesenchymal stem cells can become dermal papilla cells, aiding hair growth.
75 citations
,
August 2011 in “Journal of Investigative Dermatology” Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.
21 citations
,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
September 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Scientists successfully created fully functional hair follicles using bioengineering methods and stem cells.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
April 2023 in “Journal of Investigative Dermatology” Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
November 2022 in “Bioengineering” The method can test hair growth products using a lab-made hair-like structure that responds to known treatments.
19 citations
,
September 2019 in “British Journal of Dermatology” FOL-005 peptide can reduce human hair growth by lowering FGF7 levels.
36 citations
,
April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.
November 2022 in “Journal of Investigative Dermatology” Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
July 2025 in “The FASEB Journal” Human amniotic stem cell exosomes may effectively treat hair loss by promoting hair regrowth.
2 citations
,
September 2020 in “Biomedical materials” Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” The document concludes that while "hair follicle cloning" shows promise for unlimited donor hair, it faces challenges with consistency and safety in humans.
8 citations
,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
2 citations
,
March 2011 in “Veterinary Dermatology” FGF18 is present in beagle dog hair follicles, mainly in the inner root sheath.
February 2020 in “International Journal of Current Microbiology and Applied Sciences” Canine hair follicle cells show stem cell properties, aiding hair growth.
Hair follicle-like structures can form when specific hair cells are mixed and implanted in mice.
8 citations
,
March 2022 in “Frontiers in Cell and Developmental Biology” Human hair follicle stem cells can help treat bone loss in osteoporosis.
October 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Three-dimensional culture helps dermal papilla cells grow new human hair follicles.
May 2020 in “Research Square (Research Square)” Human stem cells can turn into functional eye cells that might help treat retinal diseases.
11 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Old hair follicles grew better when moved to a young environment.
28 citations
,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
74 citations
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August 2023 in “Frontiers in Immunology” Fibroblasts are key to wound healing by managing immune cells and forming scar tissue.
Hypoxic preconditioning helps human hair follicle stem cells survive oxidative stress.
September 2016 in “Journal of dermatological science” Adult skin cells can be used to create new hair in a lab.
3-D bioprinting can regenerate human hair follicles using bioink with collagen and fibroblasts.