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Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.

Testosterone reduces knee movement, while flutamide and finasteride increase it.

The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Higher CSF 5-HIAA levels may predict better response to serotonin re-uptake inhibitors in trichotillomania.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Blocking the KATP channel may help treat migraines.

Different ligands change the shape of the TRPV3 ion channel in unique ways.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

Acid can block TRPV3 from outside the cell but boost its function from inside.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

LHTric-1 is a specific antibody useful for studying hair and nail formation.

Bupropion SR may help treat trichotillomania.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

dAR-6–1 is a promising new treatment for hair loss that works better than minoxidil.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Behavioral interventions, especially habit reversal training, are most effective for treating trichotillomania in children.

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Deucravacitinib did not significantly improve hair regrowth in alopecia areata patients.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.