research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
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research A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle
Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
research In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells
Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature
Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
research Prospect of Stem Cell Conditioned Medium in Regenerative Medicine
Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
research Keratinocyte Cytokine Networks Associated with Human Melanocytic Nevus Development
Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
research Stem cell dynamics in the hair follicle niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling
Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
research Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Toward understanding scarless skin wound healing and pathological scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Emerging nonmetabolic functions of skin fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing
A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
research Integration Analysis of Transcriptome and Proteome Reveal the Mechanisms of Goat Wool Bending
The research identified key proteins and genes that may influence wool bending in goats.
research EGF–FGF2 stimulates the proliferation and improves the neuronal commitment of mouse epidermal neural crest stem cells (EPI-NCSCs)
EGF–FGF2 helps mouse stem cells grow and become more like nerve cells.
research 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.
research Wound Healing: A Paradigm for Regeneration
Wound healing insights can improve regenerative medicine.
research Neonatal murine skin-derived cells transplanted using a mini-chamber model produce robust and normal hair
Transplanted baby mouse skin cells grew normal hair using a new, efficient method.
research Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment
New methods for skin and nerve regeneration can improve healing and feeling after burns.
research Skin Stem Cells, Their Niche and Tissue Engineering Approach for Skin Regeneration
Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
research Quiescent Tissue Stem Cells Evade Immune Surveillance
Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research 855 Targeted deletion of crif1 in mouse skin epidermis impairs skin homeostasis
Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.