25 citations
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April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
10 citations
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August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
39 citations
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March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
36 citations
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April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
19 citations
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November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
8 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
2 citations
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January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
7 citations
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January 2021 in “Evidence-based complementary and alternative medicine” Porphyra-334 may help reduce wrinkles and promote hair growth.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
28 citations
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January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
November 2025 in “Journal of Investigative Dermatology” Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.
Using scalp stem cells can improve hair transplants.
143 citations
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September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
8 citations
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April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.
417 citations
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September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
99 citations
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January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
67 citations
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.
October 2023 in “Oncotarget” Apoptotic cells help cause hair follicle cell death during regression.
June 2025 in “Theranostics” Rapamycin-primed exosomes can significantly boost hair regrowth.
44 citations
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June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
29 citations
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December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
294 citations
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February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
13 citations
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October 2010 in “Methods in molecular biology” Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
4 citations
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February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
425 citations
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June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
253 citations
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.