124 citations
,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
April 2022 in “Biomedicine & Pharmacotherapy” CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.
11 citations
,
August 2021 in “Stem Cell Research & Therapy” The document concludes that using a person's own fat cells (SVF) can significantly increase hair thickness and density, suggesting it could be a promising treatment for hair loss.
21 citations
,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
1 citations
,
November 2021 in “Biomedicines” Understanding how acne develops in different diseases could lead to new treatments.
29 citations
,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
85 citations
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December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
10 citations
,
January 2018 in “Elsevier eBooks” Burn scars heal abnormally and more research is needed to find better treatments.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
276 citations
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December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
2 citations
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May 2023 in “Marine Drugs” Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
January 2024 in “Cosmetics” HAIR & SCALP COMPLEX may help treat hair loss by stimulating hair growth and restarting the hair cycle.
19 citations
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November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
2 citations
,
May 2015 in “International Journal of Scientific Reports” Neonatal mesenchymal stem cell therapy shows promise for treating hair loss but needs more research.
5 citations
,
June 2024 in “Developmental Cell” Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
81 citations
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September 2013 in “PLoS ONE” Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.
February 2026 in “Frontiers in Public Health” Lifestyle changes can help manage androgenetic alopecia.
February 2026 in “Plastic and Aesthetic Research” Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
February 2026 in “International Journal of Recent Surgical and Medical Sciences” Human exosomes are effective for targeted treatments but face scalability issues, while plant exosomes are cost-effective for cosmetics.
4 citations
,
December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
26 citations
,
January 2025 in “iScience” PRP helps tissue repair but lacks standard preparation methods.
480 citations
,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
25 citations
,
October 2007 in “Developmental biology” Clim proteins are essential for maintaining healthy corneas and hair follicles.
42 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
228 citations
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June 2021 in “Frontiers in Immunology” Macrophage issues cause chronic wound inflammation, but therapies can help.
August 2023 in “Journal of analytical & pharmaceutical research” Microneedle-assisted therapy with human basic fibroblast growth factor significantly regrew hair in patients with hair loss.