356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
139 citations
,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” K6hf is a unique protein found only in a specific layer of hair follicles.
57 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
13 citations
,
January 2021 in “Histochemistry and Cell Biology” Cholesterol transport in hair follicles decreases from growth to regression phase.
4 citations
,
January 2017 in “Annals of Dermatology” Tianeptine may help prevent hair loss by promoting hair growth and reducing cell death.
41 citations
,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
25 citations
,
November 2014 in “British Journal of Dermatology” Certain transporters are found in human hair follicles and may affect hair growth and loss.
8 citations
,
May 2018 in “The Journal of Allergy and Clinical Immunology” Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
149 citations
,
March 2004 in “Journal of Dermatological Science” Minoxidil boosts hair growth by increasing cell production and survival.
44 citations
,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
16 citations
,
March 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
12 citations
,
July 2017 in “Scientific reports” Researchers developed a way to study human body clocks using hair tissue, which works similarly in both healthy and dementia patients.
11 citations
,
January 2018 in “Acta dermato-venereologica” Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
6 citations
,
July 2018 in “Advances in Clinical and Experimental Medicine” Different body parts have varying levels of certain hair follicle markers.
April 2021 in “Journal of Investigative Dermatology” Leontopodium alpinum extract may help reduce hair shedding by keeping hair in the growth phase longer.
April 2019 in “Journal of Investigative Dermatology” Caffeine can protect scalp hair follicles from damage caused by UV radiation.
April 2018 in “Journal of Investigative Dermatology” Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
25 citations
,
July 2008 in “British Journal of Dermatology” CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.
166 citations
,
August 2010 in “Proceedings of the National Academy of Sciences of the United States of America” Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.
August 2024 in “Biomolecules & Therapeutics” A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
7 citations
,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
37 citations
,
March 2010 in “British Journal of Dermatology” Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
30 citations
,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
24 citations
,
January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
13 citations
,
September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
4 citations
,
April 2021 in “Experimental Dermatology” Antibiotics might affect hair growth by changing the bacteria in hair follicles.
11 citations
,
May 2016 in “Naunyn-Schmiedeberg's Archives of Pharmacology” A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.
70 citations
,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.