research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
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research Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine
Dyclonine can effectively reduce skin issues by inhibiting the TRPV3 channel.
research Advances in genetic and molecular understanding of Omenn syndrome - implications for the future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
research Platelet‐rich plasma, a powerful tool in dermatology
Platelet-Rich Plasma (PRP) shows promise for treating various skin conditions, but more research is needed to standardize its use.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Universal Dermatology: Bridging Gaps in Skin Health
Inclusive dermatology aims to provide personalized skin care for all by addressing diverse needs and disparities.
research Emerging 3D bioprinting applications in plastic surgery
3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation
Keratin 16 delays skin maturation and affects skin and hair development in mice.
research Autologous adipose tissue injection in the treatment of alopecia: A mini‐review
Injecting a person's own fat into their scalp may help regrow hair and improve hair thickness in different types of hair loss.
research Surgical Therapies
Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.
research Human Follicular Papilla Cells Carry Out Nonadipose Tissue Production of Leptin
Leptin may play a role in hair growth and hair follicle health.
research Resident human dermal γδT-cells operate as stress-sentinels: Lessons from the hair follicle
Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.
research Prevention and management of dermatological toxicities related to anticancer agents: ESMO Clinical Practice Guidelines☆
Early intervention and tailored management can reduce skin side effects from cancer treatments.
research Vitiligo - Part 2 - classification, histopathology and treatment
New vitiligo treatments focus on controlling immune damage and restoring skin color.
research Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
research Distinct Patterns of Hair Graft Survival After Transplantation Into 2 Nonhealing Ulcers: Is Location Everything?
Hair follicle transplants help heal wounds, but scar quality and hair growth vary by location.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Stem Cell-Derived and Plant-Derived Exosomes: Promising Therapeutics for Skin Healing and Regeneration
Stem cell and plant exosomes may help heal and regenerate skin.
research Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB
Human hair follicle stem cells can become smooth muscle cells using specific growth factors.
research Mesenchymal Stem Cells for the Treatment of Skin Diseases
Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
research Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma
Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
research Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions
Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
research A volar skin excisional wound model for in situ evaluation of multiple-appendage regeneration and innervation
The study concluded that the new wound model can be used to evaluate skin regeneration and nerve growth.
research Novel Follicular Unit Excision Device That Reduces Graft Injury and Improves Ergonomics in Hair Transplantation Surgery
The new hair transplant device reduces damage to hair follicles and makes surgery more comfortable for the surgeon.
research Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review
The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.