April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found a new way to isolate sweat glands from the scalp for study and culture.
August 1994 in “Toxicology in Vitro” A lab model of human skin was created to study skin tumor promoters without using actual human skin.
14 citations
,
December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
5 citations
,
January 1991 in “Acta Dermato Venereologica” Topical cyclosporin promotes hair growth.
April 2023 in “Journal of Investigative Dermatology” Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Not having enough cystatin M/E protein causes less hair growth and dry skin.
7 citations
,
October 2013 in “British Journal of Dermatology” HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.
276 citations
,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
213 citations
,
December 1994 in “Medical Entomology and Zoology” Skin cancer involves complex mechanisms, risk factors, and can be potentially prevented with strategies like dietary changes and certain compounds.
205 citations
,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
160 citations
,
April 2012 in “Journal of Cellular and Molecular Medicine” Telocytes might help with skin repair and regeneration.
147 citations
,
October 2004 in “Experimental dermatology” Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
124 citations
,
November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
82 citations
,
January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
82 citations
,
January 1994 in “Skin Pharmacology and Physiology” Hair follicles and glands significantly increase steroid absorption in skin.
69 citations
,
January 2002 in “Journal of biomedical optics” Dyes can penetrate human skin and hair follicles up to 1.2 mm deep and the sebaceous gland can store dye; Indocyanine Green lotion was made for safe dyeing and monitoring.
48 citations
,
March 2021 in “Frontiers in Cell and Developmental Biology” Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.
24 citations
,
November 2021 in “PLoS ONE” Ablative fractional laser treatment rejuvenates skin by altering gene expression and promoting wound healing and tissue regeneration.
21 citations
,
August 2007 in “Experimental Dermatology” Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.
17 citations
,
June 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
10 citations
,
March 2022 in “Communications biology” A new non-invasive method can analyze skin mRNA to understand skin diseases better.
7 citations
,
August 2017 in “Journal of dermatological science” Sorafenib causes skin reactions by increasing the number and activity of skin mast cells.
2 citations
,
April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
1 citations
,
July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Ablative fractional laser treatment rejuvenates aged skin by activating genes related to wound healing and tissue regeneration.
1 citations
,
February 2017 in “International journal of anatomy and research” Understanding fetal skin development helps diagnose congenital skin diseases.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
1 citations
,
July 2005 in “CRC Press eBooks” Topical drugs can target hair follicles to treat skin conditions more effectively.
April 2026 in “Experimental & Molecular Medicine” Mouse and human skin development share similar fibroblast timelines.