September 1999 in “Molecular Carcinogenesis” Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
16 citations
,
June 1983 in “Journal of Neurochemistry” Copper therapy improved health and enzyme activity in mice with copper deficiency.
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
135 citations
,
May 1994 in “Medical Entomology and Zoology” Mouse models help study genetic skin diseases.
1 citations
,
October 2019 in “PubMed” Removing the p75 gene in mouse skin cells didn't affect their skin or hair growth.
35 citations
,
November 1931 in “Journal of Genetics” Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.
58 citations
,
June 2006 in “Plastic and Reconstructive Surgery” Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.
March 2022 in “Osaka City University (Osaka City University)” Ovariectomy in mice affects hair growth and skin thickness, suggesting potential for obesity treatment research.
14 citations
,
February 1991 in “FEBS Letters” Introducing the rat OTC gene partially corrected OTC deficiency in mice.
4 citations
,
January 1982 in “Neuroendocrinology” Dopamine affects coat color changes in agouti mice.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
18 citations
,
June 2010 in “Cell Stress and Chaperones” Heat treatment increases hair loss in certain mice.
21 citations
,
June 2009 in “Mammalian genome” A new mutation in the Hr gene causes hair loss in mice, similar to a human hair disorder.
37 citations
,
February 2019 in “Experimental Dermatology” Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
89 citations
,
August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
June 2025 in “International Journal of Applied Pharmaceutics” A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
1 citations
,
October 1996 in “Dermatologic clinics” Adiponectin reduces inflammation and bone loss in joint replacements.
1 citations
,
June 2022 in “Experimental dermatology” The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.
5 citations
,
August 2023 in “G3 Genes Genomes Genetics” The improved genome of the African spiny mouse will help understand its tissue regeneration abilities.
578 citations
,
April 1993 in “Cell” TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
59 citations
,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
75 citations
,
March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
35 citations
,
October 2017 in “Trends in Molecular Medicine” Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
89 citations
,
March 1996 in “Proceedings of the National Academy of Sciences” CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
June 2020 in “Comparative medicine” NSG mice had the most mites, and genetic factors affect immune response and susceptibility.
Ganoderma lucidum extract and microneedle therapy promote hair growth in mice.
March 2026 in “Trends in Sciences” A mouse model was created to study hair loss similar to humans.
January 2023 in “Faculty of 1000 Research Ltd” Androgen loss may speed up hair greying.
24 citations
,
October 2022 in “Cell Regeneration” A new mouse model effectively mimics vitiligo for research and drug testing.