Introducing the OTC gene improved symptoms in mice with OTC deficiency.
8 citations
,
September 2011 in “Scanning” Multiphoton microscopy effectively images mouse skin layers and structures.
April 2018 in “Journal of Investigative Dermatology” Older mice healed wounds better but lost more weight and might have weaker immune systems afterward.
51 citations
,
January 2004 in “European Journal of Cell Biology” Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.
5 citations
,
March 2022 in “STAR Protocols” The method helps study hair follicle stem cells and calcium signals in mouse skin.
6 citations
,
October 1989 in “PubMed” Optimized conditions and specific treatments enhance the growth of hair cells from C3H mice.
86 citations
,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
19 citations
,
December 2021 in “Stem Cell Research & Therapy” Muse cells from human bone marrow help reduce symptoms of atopic dermatitis in mice.
30 citations
,
August 2016 in “Advances in radiation oncology” Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
2 citations
,
May 2018 in “Journal of Investigative Dermatology” Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.
13 citations
,
January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
11 citations
,
January 2005 in “Brazilian Journal of Medical and Biological Research” Hairless USP mice have enlarged skin cysts as they age.
21 citations
,
August 2007 in “Experimental Dermatology” Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.
September 2016 in “Journal of Dermatological Science” A gene mutation worsens skin irritation in mice due to a lack of certain fats.
9 citations
,
November 2019 in “Cell calcium” The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
April 2018 in “Journal of Investigative Dermatology” African spiny mice can regenerate skin and hair after wounds due to specific tissue mechanics.
1 citations
,
July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
2 citations
,
January 2023 in “Pharmaceuticals” Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
January 1990 in “UCL Discovery (University College London)” The guinea pig α-lactalbumin gene was successfully expressed in the mammary glands of transgenic mice.
27 citations
,
December 2013 in “Endocrinology” Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
23 citations
,
January 1985 in “Journal of Neuropathology & Experimental Neurology” Cupric chloride treatment corrected abnormal Purkinje cell development in brindled mice.
56 citations
,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
69 citations
,
May 1997 in “Veterinary Pathology” The angora mouse mutation causes long hair and hair defects due to a gene deletion.
38 citations
,
May 1971 in “Clinical genetics” A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
18 citations
,
April 2013 in “PLOS ONE” Mice with autoimmune hair loss showed signs of heart problems.
January 2004 in “Laboratory Animal Science and Administration” The hairless mutant gene causes early hair loss and affects skin and thymus development in mice.
January 2011 in “Open Collections” Mouse preputial glands are highly developed sebaceous glands that mainly secrete neutral fat droplets.
13 citations
,
March 1999 in “Biochemical Journal” Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
50 citations
,
October 1918 in “The journal of experimental zoology” Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.
29 citations
,
December 2017 in “Molecular therapy” Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.