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Mogamulizumab treatment in Sézary syndrome may cause skin issues and hair loss but can lead to a complete response.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Donor lymphocyte infusions effectively treated leukemia relapse but caused vitiligo and alopecia areata.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Nonimmunogenic forms of keratins K71 and K31 can delay and prevent alopecia areata.

NXC736 significantly reduced hair loss in mice with alopecia areata.

The new microneedle patch effectively treats alopecia areata with fewer side effects than oral medication.

The model helps understand scar contraction and develop new treatments.

Belimumab reduces disease activity, steroid use, and flares in lupus patients.

TAK-279 effectively reduces psoriasis symptoms and is safe.

VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.

BMS-470539 reduces skin fibrosis and inflammation.

Alopecia can be caused by multicentric reticulohistiocytosis.

Dupilumab helped improve skin and prevent new lesions in a child with a rare immune disorder and severe eczema.

As of December 2021, the most effective COVID-19 treatments were monoclonal antibodies and possibly early-administered convalescent plasma, while several drugs were found ineffective or were still under evaluation.

New methods improve stem cell delivery for heart disease, but challenges remain.

The treatments stopped hair regrowth in mice.

A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.

Dupilumab may help treat alopecia areata without needing high IgE levels.

Careful monitoring is crucial to prevent JC virus reactivation in lupus patients treated with rituximab.

New mouse models of Pemphigus show severe symptoms and need better treatments.

The PML protein helps prevent skin cancer in mice.

The CD44-CD49d complex boosts T cell activation and survival in autoimmune disease.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Upadacitinib improved multiple immune-related conditions in one patient.