research Role of Transepidermal and Transfollicular Routes in Percutaneous Absorption of Steroids: In vitro Studies on Human Skin
Hair follicles and glands significantly increase steroid absorption in skin.
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research Methods for quantifying intrafollicular drug delivery: a critical appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Use of the skin sandwich technique to probe the role of the hair follicles in sonophoresis
Ultrasound increases skin permeability but blocks hair follicles.
research Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients
Topical finasteride works faster and better than 17α-estradiol for postmenopausal hair loss.
research 6516 A Curious Case of Cushing Syndrome
A single steroid injection can cause serious side effects like Cushing Syndrome.
research Factors influencing hydrocortisone permeation into human hair follicles: Use of the skin sandwich system
Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
research Percutaneous Absorption of Minoxidil in Man
Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Topical absorption and systemic toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Caffeic acid skin absorption: Delivery of microparticles to hair follicles
Microparticles help caffeic acid stay longer in hair follicles for better treatment of folliculitis.
research Applications of steroid drugs entrapped in cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Topical minoxidil in the treatment of alopecia areata.
Minoxidil helps hair regrowth in alopecia, but more research needed.
research Alopecia Areata of Eyebrows— Corticosteroids
Corticosteroid injections helped eyebrow hair regrow in men with alopecia areata.
research Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man
Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
research Liposomal systems as drug delivery vehicles for dermal and transdermal applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Clobetasol Propionate, 0.05%, vs Hydrocortisone, 1%, for Alopecia Areata in Children
Clobetasol propionate, 0.05%, is more effective and safe for treating childhood alopecia areata than hydrocortisone, 1%.
research Bioavailability assessment of topical delivery systems: Effect of vehicle evaporation upon in vitro delivery of minoxidil from solution formulations
Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.
research Hyperadrenocorticism (Hyperadrenocorticoidism, Hyperadrenocorticalism, Cushing’s Disease, Cushing’s Syndrome)
Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
research Topical use of systemic drugs in dermatology: A comprehensive review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
research Peculiar hypertrichosis in a patient affected by frontal fibrosing alopecia with pseudo "fringe sign"
A woman with frontal fibrosing alopecia experienced unusual hair growth after using a specific topical lotion.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Intralesional steroids for alopecia areata
Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.
research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs
Hair follicles significantly affect the skin absorption of some drugs.
research How I Do It: Galenic Lotions for Topical Use to Cure Hair Thinning in Males and Females
Galenic lotions can effectively treat different patterns of hair thinning in men and women.
research Actualización terapéutica en corticoesteroides tópicos: clasificación, usos clínicos y efectos colaterales
Topical corticosteroids are effective for skin conditions but can have side effects.
research Skin Structure, Physiology, and Pathology in Topical and Transdermal Drug Delivery
Improving drug delivery through the skin requires understanding skin and using enhancers.
research Effects of mitotane treatment on human steroid metabolism: implications for patient management
Mitotane changes steroid breakdown, affecting cortisol availability.
research Evaluation of a topical treatment for the relief of sensitive skin
QV Face Rescue Gel effectively soothes sensitive skin and boosts collagen without causing irritation.
research Studies on the efficacy of methyl esters of n-alkyl fatty acids as penetration enhancers
Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.