9 citations
,
November 2015 in “JAMA dermatology” A 91-year-old woman's hair turned black in one spot, with skin changes underneath.
9 citations
,
June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
119 citations
,
May 1987 in “The Journal of Dermatologic Surgery and Oncology” Most patients' skin darkening after sclerotherapy fades on its own within 6-24 months.
October 1967 in “Archives of Dermatology” A 42-year-old woman had a scalp lesion that didn't cause hair loss and showed specific changes under a microscope.
56 citations
,
December 1978 in “The Journal of Dermatologic Surgery and Oncology” Transplanting small skin grafts can successfully repigment leukoderma.
1 citations
,
August 2018 in “Dermatologic Surgery”
November 2025 in “International Journal of Advanced Research” Platelet-rich plasma therapy effectively treated laser-induced skin lightening.
1 citations
,
April 2025 in “Clinical Cosmetic and Investigational Dermatology” A rare skin lesion in a 64-year-old woman was successfully treated with a laser, showing minimal redness and no return after one month.
1 citations
,
May 2007 in “Chinese Medical Journal” Complete removal of large scalp nevi is recommended to prevent complications.
November 2024 in “Karnataka Pediatric Journal” June 2023 in “International Journal of Dermatology” Lichen planus pigmentosus mainly affects middle-aged women with darker skin, is underreported, and is hard to treat.
17 citations
,
January 2014 in “Journal of Oral and Maxillofacial Pathology” Seborrheic keratosis is a common, harmless skin growth that can look like cancer, so it may need a biopsy.
12 citations
,
August 1988 in “Histopathology” The tumor likely shows dual neural crest differentiation.
2 citations
,
July 2016 in “Veterinary dermatology” Hyperaesthetic leucotrichia in horses causes painful, recurring skin lesions and hair color changes, especially in Arabian and American paint horses.
June 2021 in “Asian Journal of Medical Sciences” Vitamin B12 deficiency can cause reversible skin darkening.
12 citations
,
November 2011 in “Pediatric dermatology” A 16-year-old boy had a rare case of Becker's nevus on his face and mouth.
June 2025 in “British Journal of Dermatology” Melanocytic matricoma can look like skin cancer but is usually harmless; surgery and follow-up are advised.
7 citations
,
May 1978 in “Acta Dermato Venereologica” A 36-year-old man had unusual skin lesions on his face without hair loss.
July 2022 in “European Journal of Dermatology” Brodalumab is more effective than ustekinumab in treating psoriasis.
March 2026 in “Dermatopathology” A rare skin tumor with extra hair growth was found and safely removed from a 27-year-old woman.
5 citations
,
January 2018 in “Indian Dermatology Online Journal” A brown shadow seen in dermoscopy is a marker for lichen nitidus.
Hair turning darker can be a sign of skin cancer.
94 citations
,
October 2017 in “International Journal of Dermatology” Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.
1 citations
,
January 2022 in “Clinical dermatology review” A young man's cheek papule was identified as a benign hair follicle tumor using a skin surface microscope.
2 citations
,
March 2023 in “JAAD case reports” Hair repigmentation can indicate malignancy and should be investigated.
2 citations
,
October 2016 in “Nutrition in clinical practice” Vitamin B12 deficiency can cause facial dark spots that go away with treatment.
13 citations
,
January 2009 in “The Open Dermatology Journal” Oral pigmentation can be a sign of Addison's disease.
9 citations
,
September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.
24 citations
,
September 2008 in “Clinical and experimental dermatology” Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
June 2025 in “Australasian Journal of Dermatology” Pigmented rings with central clearing help diagnose melasma more accurately.