research Integrative Comparison of the Role of the PHOSPHATE RESPONSE1 Subfamily in Phosphate Signaling and Homeostasis in Rice
OsPHR3 can help breed rice that efficiently uses phosphate without growth issues.
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research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Drug Repurposing for Rare Diseases
Drug repurposing offers a faster, cheaper way to find treatments for rare diseases.
research Medical Hair Restoration Brings REVVup to HairLossSpecialists
Medical Hair Restoration added a non-surgical hair therapy program to help people with early hair loss.
research Assistants' CornerAssistants' Program for the 7th Annual Meeting of the International Society of Hair Restoration SurgeryStaffing: Continued responses to the article, “Staffing the Way I Like It,” Carlos Puig, DO (Forum, Vol. 9, No. 4, July/August 1999)Hydrogen Peroxide Revisited
research Body temperature-responsive Janus patches accelerate diabetic wound regeneration via coupling mechanical transduction and biochemical pathways
research Dose‐response of human follicles during laser‐based hair removal: Ex vivo photoepilation model with classification system embracing morphological and histological features
Higher light doses cause more damage to hair follicles, predicting better hair removal results.
research Aggressive treatment in paediatric or young patients with drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is associated with future development of type III polyglandular autoimmune syndrome
Aggressive treatment in young patients with certain drug reactions may lead to multiple autoimmune diseases later.
research Effect of finasteride on ovulation induction in nonresponder (hyperandrogenic) polycystic ovary syndrome (PCOS) women
research Directional Pressure Pump Hydrogel Transmission Platform Provides Bionic Contractile Force and Remodels the Healing Process for Diabetic Mechanically Dynamic Wounds
The hydrogel platform speeds up healing in diabetic wounds.
research A smart deoxyribozyme-based fluorescent sensor for in vitro detection of androgen receptor mRNA
Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.
research AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma
AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.
research SHAREABLE RESOURCE
Different health issues need specific treatments for effective management.
research Complex Regional Pain Syndrome I (Reflex Sympathetic Dystrophy)
CRPS type I is a complex pain condition with no proven cure, requiring personalized treatment.
research Complex Regional Pain Syndrome Type I : measurements and treatment
CRPS I is complex, linked to immune and nerve issues, and needs comprehensive treatment.
research Transgenic mouse models support HCR as an effector gene in the PSORS1 locus
The HCR gene contributes to psoriasis risk.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
research Multifunctional and immunoregulatory microenvironment-responsive hydrogel for whole course management of infected diabetic wounds
The ATAN-Met hydrogel helps heal infected diabetic wounds by promoting tissue regeneration and fighting bacteria.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Heed Early Signs
Pay attention to early warnings.
research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)
Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
research Minireview: vitamin D receptor: new assignments for an already busy receptor. - eScholarship
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
research Surface-induced mechano-regulation of macrophages: emerging strategies for immunotherapy
Mechanical surface cues can control macrophage behavior for better immunotherapy and tissue healing.
research Assessing patient satisfaction among ABHRS surgeons: Opportunities to improve
ABHRS surgeons got higher ratings on Healthgrades and lower on Yelp compared to nonsurgeons, with training affecting satisfaction differently across platforms.
research Repurposed Drugs
Repurposing existing drugs can save time and money in finding new treatments.
research ς1Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward
Neuroactive steroids affect cocaine's rewarding effects through the ς1 receptor.
research A New Heterozygous Variant of c.1225_1227delTTC (p.Phe409del) in Insulin Receptor Gene Associated with Severe Insulin Resistance and Hyperandrogenemia in an Adolescent Female with Type A Severe Insulin Resistance Syndrome
A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.
research The heme-responsive PrrH sRNA regulatesPseudomonas aeruginosapyochelin gene expression
PrrH sRNA controls pyochelin gene expression in Pseudomonas aeruginosa based on heme levels.
research Peer Review #1 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers criticized the study for its assumptions, social media data collection issues, and lack of comparison to existing methods.