research Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal?
Enhancing antioxidant responses can improve treatments for various diseases.
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research A mechanical-assisted post-bioprinting strategy for challenging bone defects repair
The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
research Response to Letter: “Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss”
Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.
research Modulating mechanosensory afferent excitability by an atypical mGluR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
research Uso de medicina biorreguladora de sistemas en paciente canino alopécico, asociado a quimioterapia metronómica realizada para el manejo de carcinoma de células hepatoides.
Biorregulatory therapy significantly improved the dog's health, reversing previous issues and eliminating the need for ongoing medication.
research A novel actor in skin biology: the mineralocorticoid receptor
Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
research A case of bullous pemphigoid in a malignant melanoma patient following an increased Th2/Th1 ratio in peripheral blood cells after nivolumab treatment
Combining hair transplantation with PRP is more effective for treating hair loss than hair transplantation alone.
research Hypoxic Preconditioning Prevents Oxidative Stress-Induced Cell Death in Human Hair Follicle Stem Cells.
Hypoxic preconditioning helps human hair follicle stem cells survive oxidative stress.
research Hairy‐Skin‐Adaptive Viscoelastic Dry Electrodes for Long‐Term Electrophysiological Monitoring
The new electrode improves long-term monitoring on hairy skin by reducing motion issues and is easy to use.
research Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
Reducing PIEZO1 speeds up wound healing.
research Iododerma in pregnancy secondary to iodinated multivitamins
A man developed an allergic skin reaction to a rosacea treatment and improved after stopping the medication and receiving allergy-specific care.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
research Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development.
RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.
research Investigation of the Development of Hypersensitivity and Hyperalgesia After Repeated Application of Platelet-Rich Plasma in Rats: An Experimental Study
Repeated use of platelet-rich plasma in rats caused increased pain sensitivity.
research Enrichment and characterization of human dermal stem/progenitor cells using collagen type IV
Scientists identified a group of human skin cells with high growth and regeneration potential.
research Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Magneto-responsive biocomposites in wound healing: from characteristics to functions
Magneto-responsive biocomposites help heal wounds faster and better.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research RSPO1, a potent inducer of pancreatic β cell neogenesis
RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.
research Androgen receptor modulators: a review of recent patents and reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research Purification and characterization of an immuno-stimulatory compound from the water extract of royoporus badius (Pers.) A.B. De.
A new compound from Royoporus badius activates immune cells and induces inflammatory responses.
research Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese
Polygenic risk scores can predict the risk and outcomes of benign prostatic hyperplasia.
research DrugNet: Network-based drug–disease prioritization by integrating heterogeneous data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Alopecia: Association with Resistance to Thyroid Hormones
A specific thyroid hormone resistance mutation may be linked to different types of hair loss.
research Reply
The Thr1022Ala variant in the hairless gene is not a disease-causing mutation.
research Synergistic antioxidant-antimicrobial-immunomodulatory self-healing “radical sponge” hydrogel for diabetic wound regeneration via microenvironment reprogramming mediated by coordinated MAPK suppression and PI3K-AKT activation
The hydrogel helps heal diabetic wounds by combining antibacterial, antioxidant, and immune-boosting effects.
research Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons
GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
research P97: Epidermal growth factor receptor inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of immune privilege
research Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses
Recent selection on immune response genes was identified across seven ethnicities.
research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.