26 citations
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March 2006 in “Endocrine, metabolic & immune disorders. Drug targets” This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
1 citations
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January 2009 in “X-ray Structure Analysis Online” A new compound was made that might help treat diseases related to male hormones.
21 citations
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September 2013 in “Current medicinal chemistry” HAC and BAC improve skin targeting and reduce diffusion without causing irritation.
105 citations
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January 2009 in “Medicine” Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
35 citations
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August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
2 citations
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October 1951 in “Journal of gerontology” Patients with hair pigment loss and hair loss may have altered pantothenic acid metabolism.
26 citations
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January 1983 in “PubMed” Trichothiodystrophy involves brittle hair due to low sulfur amino acids, not a transport defect.
January 1981 in “The Journal of Toxicological Sciences” Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.
May 2026 in “BMC Medicine” ACOD1 deficiency worsens hair loss by causing cell aging and mitochondrial problems, but 4-OI may help.
1 citations
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June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” Chemical modifications can alter hair's stability and flexibility, with hydrophobic interactions helping maintain structure in humid conditions.
1 citations
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September 2001 in “PubMed” Acitretin treats severe skin conditions but requires careful monitoring due to serious side effects.
May 2022 in “Endocrine Abstracts” Cyproterone acetate therapy improved hair loss and reduced testosterone levels in a menopausal woman.
6 citations
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January 1977 in “Archives of dermatological research”
June 2025 in “Research Square (Research Square)” HAIR-AN syndrome mainly affects obese women and can be improved with early diagnosis and treatment using insulin-sensitizing agents.
39 citations
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January 1980 in “Dermatology” Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.
7 citations
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February 2012 in “British Journal of Dermatology” TH antibodies in vitiligo and AA patients recognize the same protein parts.
46 citations
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April 1987 in “Brain Research” Hair-follicle nerves in cats' spinal cords can be inhibited by GABA-related connections.
February 2025 in “International Journal of Cosmetic Science” A new amino acid derivative, ATS, improves hair texture and moisture, making it easier to straighten curly hair.
Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.
1 citations
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January 2014 SAHA syndrome links oily skin, acne, excess hair, and hair loss in women, similar to PCOS.
April 2018 in “Journal of Investigative Dermatology” Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
December 2004 in “Neuropsychopharmacology” Long-term alcohol exposure alters brain receptor function differently in various brain regions.
Alpha-ketoglutaric acid may help treat aging and age-related diseases.
86 citations
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February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
76 citations
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May 2011 in “Liver transplantation” Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.
4 citations
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December 2013 in “Acupuncture and related therapies” N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.
3 citations
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January 2019 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” Idiopathic hirsutism is the most common cause, followed by PCOS, and insulin resistance should be checked in patients with acanthosis nigricans.
11 citations
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February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
Hydrophobic modifications make human hair less affected by water.
7 citations
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March 2018 in “Psychiatry and Clinical Psychopharmacology” Valproate can cause brain swelling with high ammonia levels, possibly underreported, especially in psychiatric patients.