April 2017 in “Journal of Dermatological Science” Zinc deficiency disrupts hair growth and regeneration, but can be reversed with zinc supplementation.
5 citations
,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.
32 citations
,
February 2024 in “Growth Hormone & IGF Research” Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
July 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” April 2020 in “BMC endocrine disorders” A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
12 citations
,
October 2001 in “Pediatric Dermatology” Satoyoshi syndrome symptoms can improve with corticosteroids and surgery.
103 citations
,
July 2001 in “Proceedings of the National Academy of Sciences” TGFβ1 expression in skin causes hair loss and skin thickening, but these effects are reversible.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
24 citations
,
May 1951 in “Endocrinology” Adrenocorticotropic hormone inhibits growth and affects body composition in male rats.
32 citations
,
January 1971 in “Annals of Internal Medicine” People with anhidrotic ectodermal dysplasia may get severe bronchitis if exposed to dust.
January 2012 in “Journal of Cosmetics, Dermatological Sciences and Applications” The document concluded that certain clinical signs and hair growth tests help diagnose Short Anagen Syndrome.
26 citations
,
September 1969 in “The American journal of medicine” Cronkhite-Canada Syndrome often leads to death within 6-18 months.
34 citations
,
August 2005 in “Veterinary Dermatology” Goats may need lifelong zinc supplements due to hereditary zinc absorption issues.
32 citations
,
May 2012 in “PloS one” Thymic transplantation normalized some T-cells but not others, maintaining immune function.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.
2 citations
,
January 2006 in “Indian Journal of Veterinary Pathology” Trichophyton mentagrophytes causes skin issues and nutrient deficiencies in young sheep, especially in winter.
4 citations
,
May 2022 in “Journal of Nepal Medical Association” Steroids, infection management, and nutritional support can significantly improve symptoms of Cronkhite-Canada Syndrome.
CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
27 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”
81 citations
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June 2012 in “European journal of human genetics” Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
1 citations
,
July 2019 in “Case reports in dermatology” A Thai boy was diagnosed with a rare hair disorder causing hair thinning and shedding.
1 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.
2 citations
,
August 2017 in “British Journal of Dermatology” Hair loss in Cronkhite-Canada syndrome may be due to an autoimmune response.
88 citations
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October 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Patients with this syndrome can have different responses and worsening resistance to treatment over time.
111 citations
,
April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
5 citations
,
February 1981 in “Experientia” A new gene causes hairlessness and skin cysts in rats.
12 citations
,
January 2001 in “Der Hautarzt” Trichorhinophalangeal syndrome causes hair, facial, and bone issues, with no specific treatment beyond gentle care.
2 citations
,
August 2022 in “Federal Practitioner” A severe medication reaction required long treatment and led to hair loss and thyroid issues.