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Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways

research Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways

194 citations , March 2003 in “American Journal of Pathology”

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

research Drug-Induced Hair Loss and Hair Growth

147 citations , April 1994 in “Drug Safety”

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

research Paneth Cells in Intestinal Homeostasis and Tissue Injury

146 citations , June 2012 in “PLoS ONE”

Paneth cells help support stem cells and aid tissue regeneration after injury.

research Transplantation immunology: Solid organ and bone marrow

139 citations , February 2010 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Transplant success has improved with better immunosuppressive drugs and donor matching.

research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging

132 citations , January 2017 in “International Journal of Molecular Sciences”

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

research Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control

127 citations , December 2005 in “Experimental Dermatology”

Stress can stop hair growth in mice, and treatments can reverse this effect.

research Drug-Induced Skin, Nail and Hair Disorders

114 citations , January 2007 in “Drug Safety”

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Pityrosporum Species as a Cause of Allergy and Infection

research Pityrosporumi> species as a cause of allergy and infection

89 citations , May 1999 in “Allergy”

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

research Identification of drug-specific public TCR driving severe cutaneous adverse reactions
88 citations , August 2019 in “Nature communications”

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

research Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism
68 citations , November 2015 in “The Journal of Allergy and Clinical Immunology”

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

research T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities
66 citations , March 2018 in “British journal of dermatology/British journal of dermatology, Supplement”

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

research Anti-inflammatory, cyclooxygenase inhibitory and antioxidant activities of standardized extracts of Tridax procumbens L.
61 citations , September 2010 in “Fitoterapia”

Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.

research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease
60 citations , September 2013 in “Alimentary Pharmacology & Therapeutics”

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

research Targeting lymphoid-derived IL-17 signaling to delay skin aging
59 citations , June 2023 in “Nature Aging”

Blocking IL-17 signaling may reduce skin inflammation and delay aging.

research A Prospective Study of Cutaneous Adverse Events Induced by Low-Dose Alpha-Interferon Treatment for Malignant Melanoma
56 citations , January 2004 in “Dermatology”

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

research Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms
52 citations , September 2018 in “International Journal of Molecular Sciences”

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

research Trichodysplasia of immunosuppression treated with oral valganciclovir
41 citations , December 2008 in “Journal of the American Academy of Dermatology”

Oral valganciclovir improved a patient's skin condition caused by immunosuppression.

research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
38 citations , September 2017 in “Oncologist”

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

research Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
36 citations , July 2020 in “Frontiers in Medicine”

Spironolactone might help protect against severe lung problems in COVID-19 patients.

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse
36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

research Three cases of immune‐mediated adnexal skin disease treated with cyclosporin
36 citations , January 2006 in “Veterinary Dermatology”

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

research Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1
34 citations , November 2010 in “Development”

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

research New onset of alopecia areata in a patient with SARS‐CoV‐2 infection: Possible pathogenetic correlations?
32 citations , March 2021 in “Journal of cosmetic dermatology (Print)”

COVID-19 infection may trigger alopecia areata in some patients.

research Medication-Induced Repigmentation of Gray Hair: A Systematic Review
28 citations , December 2019 in “Skin appendage disorders”

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation?
28 citations , November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.

research Reversible Alopecia Universalis During Treatment with PEG-Interferon and Ribavirin for Chronic Hepatitis C
27 citations , April 2005 in “Journal of Chemotherapy”

Some patients may experience temporary total hair loss from hepatitis C treatment with PEG-interferon and ribavirin.

research Modeling cell–cell communication for immune systems across space and time
20 citations , November 2019 in “Current Opinion in Systems Biology”

The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.

research Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
19 citations , May 2020 in “Cells”

Substance from human umbilical cord blood cells promotes hair growth.

research Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata
19 citations , January 2018 in “Scientific Reports”

Non-immune factors play a significant role in alopecia areata.

research Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice
18 citations , April 2013 in “PLOS ONE”

Mice with autoimmune hair loss showed signs of heart problems.

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