research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
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300-330 / 1000+ resultsresearch TGF-α Is Widely Expressed in Differentiated as well as Hyperproliferative Skin Epithelium
research Nucleocytoplasmic Communication in Progeria
Defective nuclear transport may cause gene expression changes in Progeria.
research Regulation of secondary hair follicle cycle in cashmere goats by miR-877-3p targeting IGFBP5 gene
miR-877-3p can improve cashmere quality by regulating hair growth in goats.
research Differences in Human Skin Between the Epidermal Growth Factor Receptor Distribution Detected by EGF Binding and Monoclonal Antibody Recognition
research HMGB1 promotes hair growth via the modulation of prostaglandin metabolism
A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
research Integrated multiple machine learning and Mendelian randomization reveal LTF gene as a prognostic biomarker for nonspecific orbital inflammation
The LTF gene may help predict and manage nonspecific orbital inflammation.
research Icariside II inhibits gastric cancer progression by suppressing the Wnt/β-catenin signaling pathway
research 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes
Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.
research Discovery of Four New FGF5 Variants Causing Long Hair in the Dog
Four new FGF5 gene variants cause long hair in dogs.
research Characterization of novel TMEM173 mutation with additive IFIH1 risk allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Against the Rules: Human Keratin K80
Keratin K80 is an ancient protein found in various tissues, important for cell structure and tissue differentiation.
research Letter from Brisbane [Letters to editor]
A Japanese patient with a rare genetic disorder had a less severe case than others, suggesting other factors may affect symptoms.
research 1326 Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research Deletion of an enhancer in FGF5 is associated with ectopic expression in goat hair follicles and the cashmere growth phenotype
A genetic change in the FGF5 gene affects hair growth in cashmere goats.
research Der Einfluss von pdHGF auf die Wundheilung
pdHGF speeds up wound healing and hair growth.
research Faculty Opinions recommendation of Hair cycle resting phase is regulated by cyclic epithelial FGF18 signaling.
FGF18 controls hair cycle rest and growth phases.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
research Cell‐free transcriptomic profiles and mechanism insights in female androgenetic alopecia
DNAJB9 cfRNA could help diagnose and treat female hair loss.
research Injectable platelet-rich fibrin promotes proliferation and trichogenic inductivityof dermal papilla cells through activating TGF-β/Smad signaling pathway
Injectable platelet-rich fibrin is better than platelet-rich plasma for promoting hair growth.
research Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin
Follistatin helps hair growth and cycling, while activin prevents it.
research Safety and efficacy analysis of liposomal insulin-like growth factor-1 in a fluid gel formulation for hair-loss treatment in a hamster model
Liposomal IGF-1 safely and effectively treats hair loss in hamsters.
research FGF signaling for hair cycle resting phase alleviates radiation alopecia
FGF18 treatment during hair's resting phase can protect against hair loss from radiation.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research 130 Expression of nidogen1 in basal cell carcinoma
Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
research EGFR : stopping stathmin to start the cycle
EGFR helps hair follicles transition properly by controlling Stathmin levels.
research The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin
Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research A Splice Site Mutation in the Gene of the Human Type I Hair Keratin hHa1 Results in the Expression of a Tailless Keratin Isoform
A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
research Novel TMEM173 Mutation and the Role of Disease Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.