December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
384 citations
,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
308 citations
,
September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
301 citations
,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
295 citations
,
March 2016 in “Life Sciences” Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
159 citations
,
October 2015 in “Science Advances” Blocking JAK-STAT signaling can lead to hair growth.
145 citations
,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
96 citations
,
February 2007 in “The Journal of Clinical Endocrinology & Metabolism” Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.
82 citations
,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
67 citations
,
November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
60 citations
,
December 2015 in “Lasers in Medical Science” Low-level laser therapy is safe and can increase hair growth for male and female pattern hair loss.
55 citations
,
March 2015 in “Carcinogenesis” WNT10A helps esophageal cancer cells spread and keep renewing themselves.
52 citations
,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
45 citations
,
November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
32 citations
,
July 2018 in “Scientific Reports” Essential-oils-cobalt improves goat growth and product quality.
32 citations
,
January 2007 in “KARGER eBooks” Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.
28 citations
,
March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
20 citations
,
February 2017 in “International Journal of Dermatology” Honokiol helps protect skin from damage and aging caused by cigarette smoke.
12 citations
,
October 2012 in “Dermatologic Clinics” Low-Level Laser Therapy and other light treatments for hair growth lack strong evidence and need more research.
9 citations
,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
6 citations
,
July 2015 in “International Journal of Dermatology” Trichoepitheliomas can be hard to distinguish from other skin conditions and often start in teenage years.
4 citations
,
March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
3 citations
,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
1 citations
,
October 2023 in “Life science alliance” Pantethine may boost the immune system's ability to fight sarcoma.
1 citations
,
January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” Placenta polypeptide injection is a safe and effective treatment for sensitive skin.
December 2025 in “International Journal of Pharmacology” iPSC-derived artificial platelets show promise for consistent and effective regenerative therapies.
June 2024 in “Research Square (Research Square)” Increased cell death and reduced cell growth in hair follicles contribute to baldness.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.