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Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.

PCOS is linked to low-grade chronic inflammation.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

Mutations in β1 integrins cause embryonic death but have milder effects on skin.

SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.

Sintilimab with chemotherapy improves survival and response in advanced lung cancer but increases some side effects.

An elderly woman developed severe skin discoloration after homeopathic knee injections, but the exact cause is unclear.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

Biomimetic nanovesicles can speed up diabetic wound healing by regulating immune cell behavior and metabolism.

Activating TLR3 helps improve skin and hair follicle regeneration after wounds.

IL-17 and IL-23 inhibitors can cause unexpected hair loss in some patients.

New therapies like JAK inhibitors and stem cells show promise for treating vitiligo.

Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.

Topical immunotherapy for alopecia areata may work by creating immune cell clusters in the skin.

Anti-IL17A therapy reduced venous leg ulcer size by 64% without major side effects.

Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

Upadacitinib may effectively treat resistant lichen planopilaris.

Activating GLI1 signaling without primary cilia could be a promising treatment for neuroblastoma.

High levels of NEDD4-TV3 and IGF-1 may predict and contribute to keloid formation.

Blocking IL-8 can reduce skin rashes from cancer treatment.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Dupilumab can both heal and cause hair loss.

IFN-γ production by CD4 T cells is crucial for causing alopecia areata.

High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.

The new treatment effectively reduces artery blockage and inflammation in atherosclerosis.

Herbal extract may help treat certain types of hair loss.