232 citations
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December 2011 in “Journal of the American Academy of Dermatology” Understanding and targeting specific molecules can help reduce scarring and promote scar-free healing.
90 citations
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
75 citations
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September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
60 citations
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December 2003 in “Journal of Investigative Dermatology” K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.
56 citations
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September 2016 in “Pharmaceutical Research” The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.
53 citations
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July 2009 in “Cancer Research” Blocking certain proteins can reduce skin inflammation caused by cancer treatment.
42 citations
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December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
38 citations
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January 2017 in “Mediators of Inflammation” Platelet-released growth factors can reduce inflammation in joint disease.
37 citations
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May 2018 in “Transgender health” Oral estradiol works for many transgender women but needs personalized dosing and monitoring.
32 citations
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July 2017 in “Molecular diagnosis & therapy” MicroRNA-21 could help diagnose and treat skin fibrosis.
31 citations
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December 2021 in “Materials” The gels improved wound healing in diabetic mice but need human trials.
29 citations
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March 2014 in “PloS one” Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.
28 citations
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June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
21 citations
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December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
18 citations
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June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
15 citations
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September 2014 in “PloS one” The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.
14 citations
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November 2019 in “Mediators of inflammation” IL-6 from stem cells helps repair skin and grow hair.
13 citations
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May 2019 in “Evidence-based Complementary and Alternative Medicine” Callicarpa nudiflora extract speeds up wound healing in scalded rats.
13 citations
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November 2017 in “Neurotoxicity research/Neurotoxicity resarch” Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.
13 citations
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July 2015 in “Archives of dermatological research” N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.
12 citations
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January 2018 in “Journal of Clinical Laboratory Analysis” Certain IL-18 gene variations may increase the risk of alopecia areata.
12 citations
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April 2017 in “Experimental and Therapeutic Medicine” Patients with severe active alopecia areata have lower CD200 expression and an imbalance in their immune system.
11 citations
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July 2022 in “Journal of Materials Science: Materials in Medicine” A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.
11 citations
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October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
11 citations
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November 2015 in “Experimental Dermatology” The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
10 citations
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May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
8 citations
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June 2022 in “Cosmetics” Coffee berry extract may help slow skin aging and prevent hair loss.
8 citations
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January 2021 in “Bulletin of Experimental Biology and Medicine” ATP and IL-10 levels in hair follicles relate to follicle length and hair growth, with differences in alopecia patients.
7 citations
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January 2022 in “Scientific Reports” Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.
7 citations
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October 2018 in “South African journal of botany” Clausena anisata may be effective in treating acne due to its ability to fight bacteria, reduce inflammation, and possibly lower sebum production.