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ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

The G allele of IFITM3 rs12252 is linked to more severe COVID-19.

IL-18 signaling helps mature Tregs move into the thymus.

Hair shaft changes may be linked to CCCA, but their role is unclear.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Overexpression of LRIG3 in skin causes hair loss.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Integrin-linked kinase is crucial for normal skin healing.

Toll-like receptor 3 helps repair the skin barrier after UV damage.

A novel CLDN1 mutation in a 2-month-old with NISCH showed improvement with symptom management.

LRIG1 is linked to better survival in Merkel cell carcinoma.

Skin cells control immune cell placement, helping the skin respond better to challenges.

ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

IL-18 signaling helps mature Tregs move into the thymus.

New laser particles can track thousands of cells in 3D models, improving single-cell analysis.

p120-catenin helps control skin inflammation by regulating cadherin levels.

hsa_circ_0002980 can help stop liver cancer cells from growing and spreading.

IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

A gene mutation in mice causes skin defects and early death.

The updated criteria improve the accuracy of diagnosing lupus.

NM2 and RLC phosphorylation are essential for normal inner ear hair cell function.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

Primary cilia affect the size and oil production of eye glands but not the oil's makeup.

LC-OCT is an effective new method for diagnosing classic lichen planopilaris.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.