research Melatonin in the skin: synthesis, metabolism and functions
Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
Search
for
Sort by
Research
720-750 / 1000+ results research Characterization of Hair Follicle Bulge in Human Fetal Skin: The Human Fetal Bulge Is a Pool of Undifferentiated Keratinocytes
research Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature
Developing human skin has immune cells with memory-like features.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Clinical Snippets
Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
research Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice
Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.
research Micro-Injury Induces Hair Regeneration and Vitiligo Repigmentation Through Wnt/ β-Catenin Pathway
Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.
research Is increased constitutive skin and hair pigmentation an early sign of puberty?
Darker skin in 10-year-old girls may be an early sign of puberty.
research ‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype
Stromal cells in melanoma promote tumor growth and spread.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Cell proliferation during fibre growth initiation in ferret hair follicles
Ferret hair growth starts between 0 and 4 days after melatonin treatment, with cell growth peaking in the hair germ and declining as the hair matures.
research GENOTYPE ? PHENOTYPE CORRELATIONS IN CUTANEOUS MELANOMA PATIENTS CARRIER OF THE MITF p.E318K PATHOGENIC VARIANT
MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.
research Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype
Aging reduces dermal sheath cells, affecting youthful skin appearance.
research Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (Wsh) homozygotes
Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.
research Human skin color: Origin, variation and significance
Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
research An introduction to skin disease in melanin rich skin
Melanin-rich skin has unique challenges in diagnosing and treating skin diseases.
research Lentiginous melanoma. A clinically malignant entity that histopathologically seems benign. Case study harbouring BRAF V 600R mutation
A clinically suspected melanoma appeared benign under the microscope but was confirmed by specific tests and a rare mutation.
research The developing immune network in human prenatal skin
Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
research Finasteride inhibits melanogenesis through regulation of the adenylate cyclase in melanocytes and melanoma cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Small Intestinal Organoid-Derived SP Cells Contribute to Repair of Irradiation-Induced Skin Injury
Intestinal stem cells can help repair skin damage from radiation.
research Nevus psiloliparus: Newly described histopathological features from transverse sections
Nevus psiloliparus lacks mature hair follicles but keeps other skin structures intact.
research Stem cells in embryonic skin development
The origins of many adult skin stem cells are still mostly unknown.
research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
research Abstract 81
Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
research Author response: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Moles may stop growing because of cell cooperation, not just because of aging cells.
research Effect of mesenchymal stem cells on reducing melanin levels in response to UV radiation in male C57BL/6 mice
Mesenchymal stem cells may help reduce melanin in UV-exposed mice.
research The Majority of Multipotent Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation
Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
research Targeting the (Un)differentiated State of Cancer
Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
research Quercetin stimulates melanogenesis in hair follicle melanocyte of the mouse.
Quercetin boosts melanin production in mouse hair follicles.