research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
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research Regulatory T Cells: the Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine
Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
research Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
research Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases
Vitamins A, B3, C, D, and E can improve skin health and immunity.
research Macrophages are necessary for skin regeneration during tissue expansion
Macrophages are essential for successful skin growth in reconstructive surgery.
research Skin diseases associated with atopic dermatitis
People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
research Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Microencapsulated cell tracking
Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase helps keep skin healthy by reducing inflammation.
research A comparative analysis of immune privilege in pregnancy and cancer in the context of checkpoint blockade immunotherapy
The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
research Cell death in skin function, inflammation, and disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research T-cell “induced-self” MHC class I/peptide complexes may enable “de novo” tolerance induction to neo-antigens occurring outside of the thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
research Impaired responses of peripheral blood mononuclear cells to T-cell stimulants in alopecia areata patients with a poor response to topical immunotherapy
Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.
research Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model
Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.
research Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model
Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.
research A case of systemic mastocytosis - an ultrastructural and immunohistochemical study of the dermal mast cells in relation to activation of the epidermal melanin unit
Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.
research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets
Choosing the right method to separate skin layers is key for good skin cell research.
research 272 Structural changes in human skin after topical application of glucocorticoids assessed by in vivo imaging technologies
Topical glucocorticoids thin the skin and change collagen structure.
research Receptor tyrosine kinase Kit action in skin melanocytes: is it exclusively cell autonomous?
KIT's role in skin cells is not entirely independent, as other cells can influence its function.
research Construction strategies of skin organoids: A review
A unified framework is needed to improve skin organoid construction for research and clinical use.
research Image 1_Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata.pdf
Farudodstat can prevent hair follicle immune damage linked to alopecia areata.
research Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance
Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
research Cell-Laden Gel Biomimetic Skin Promotes Full-Thickness Skin Wound Regeneration
The new biomimetic skin heals wounds faster and better than traditional treatments, without scarring.
research Stem Cell-Derived and Plant-Derived Exosomes: Promising Therapeutics for Skin Healing and Regeneration
Stem cell and plant exosomes may help heal and regenerate skin.
research Role of skin microbiome and exosomes in Hair regeneration and disorders in diseases like Alopecia, Acne: A comprehensive review
Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
research Immune Microenvironment of Hair Follicles in Tumor Immunotherapy
Tumor immunotherapy can cause hair loss by disrupting hair follicle immunity.