6 citations
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January 2021 in “Frontiers in Immunology” Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.
286 citations
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June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
1 citations
,
July 2025 in “Journal of Investigative Dermatology” IL-27 may help prevent hair loss by creating immune-suppressing cells.
1 citations
,
August 2023 in “Biomolecules” Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.
March 2025 in “Journal of Education Health and Sport” Alopecia areata causes hair loss due to immune issues, and while new treatments show promise, no universally effective solution exists yet.
January 2025 in “Dermatology Research and Practice” Higher activity in lichen planopilaris is linked to certain immune and tissue genes.
July 2024 in “Journal of Investigative Dermatology” Expanding regulatory T cells may help treat alopecia areata by reducing harmful immune cells.
April 2023 in “Journal of Investigative Dermatology” Higher PD-1 levels are linked to fewer immune cells in hair follicles in alopecia areata.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
November 2025 in “The Journal of Immunology” Hair follicle stem cells help heal wounds by turning certain immune cells into ones that reduce inflammation.
22 citations
,
September 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
September 2025 in “Frontiers in Immunology” Atopic dermatitis and alopecia areata share immune and genetic factors, and targeted therapies may help both.
January 2023 in “Karger Kompass. Dermatologie” Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
20 citations
,
August 2007 in “Molecular therapy” Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.
15 citations
,
May 1999 in “Journal of Investigative Dermatology” Alopecia areata is complex, with genetic and immune factors, and animal models are key for future treatment research.
10 citations
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November 2017 in “Skin Appendage Disorders” Erosive pustular dermatosis in elderly people may be linked to aging immune systems and skin damage.
2 citations
,
January 2010 in “Case Reports in Medicine” Relapsing polychondritis might be linked to alopecia areata due to immune system factors.
Thymoma with alopecia areata may be linked to abnormal immune cells.
January 2023 in “Annals of dermatology/Annals of Dermatology” A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.
57 citations
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June 2018 in “Nutrients” Celiac disease can cause skin problems that may get better with a gluten-free diet.
2 citations
,
December 2007 in “Microbial pathogenesis” Anthrax bacteria can infect and destroy hair follicles in mice, but the immune system eventually clears the infection.
1 citations
,
January 2023 in “Portuguese Journal of Dermatology and Venereology” JAK inhibitors effectively treat skin conditions and topical forms are safer.
32 citations
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December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
7 citations
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January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
November 2025 in “BMC Genomics” Genetic differences in sheep affect wool type, with fat and immune genes influencing hair traits.
September 2020 in “Journal of Investigative Medicine” Omics techniques are needed to understand the scalp microbiome's role in alopecia areata for new treatments.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
December 2025 in “Academic Journal of Science and Technology” Mesenchymal stem cells can effectively aid skin healing and anti-aging.
62 citations
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April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
29 citations
,
August 2008 in “Current Opinion in Pediatrics” Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.