research Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction
Advances in mechanobiology and immunology could lead to scarless wound healing.
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research How Our Microbiome Influences the Pathogenesis of Alopecia Areata
Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.
research SnapshotDx Quiz: February 2018
Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.
research The immunology of the porcine skin and its value as a model for human skin
Porcine skin is very similar to human skin, making it a useful model for research.
research Lymphocytes, neuropeptides, and genes involved in alopecia areata
Alopecia areata is an autoimmune disease where T cells attack hair follicles.
research Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris
Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.
research A Nonredundant Human Protein Chip for Antibody Screening and Serum Profiling
The technology can help diagnose and subtype autoimmune diseases by identifying specific autoantibodies.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Trained Immunity and Local Innate Immune Memory in the Lung
Lung immune cells can be trained to better fight infections after a virus.
research The role of the microbiome in scalp hair follicle biology and disease
The scalp's microorganisms significantly affect hair health and disease.
research Vitiligo and alopecia areata: apples and oranges?
Vitiligo and alopecia areata may have similar causes despite their differences.
research Frontiers in alopecia areata pathobiology research
The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Significance of stress keratin expression in normal and diseased epithelia
Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
research Exploiting Unique Features of Microneedles to Modulate Immunity
Microneedles offer a promising, painless, and efficient way to deliver vaccines and therapies directly to the skin.
research A “hair‐raising” history of alopecia areata
The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.
research Report from the Cicatricial Alopecia Colloquium
More research is needed to understand and treat cicatricial alopecias.
research Assessment of Cytokine-Mediated Signaling Pathway Dysregulation in Arm Skin After CO2 Laser Therapy
CO2 laser treatment for aging skin significantly changes immune system-related genes.
research The Multi-Faceted Role of Gut Microbiota in Alopecia Areata
Gut bacteria may influence hair loss in alopecia areata.
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
research Good efficacy achieved by baricitinib in the treatment of anti-MDA5 antibody-positive dermatomyositis with alopecia areata
Baricitinib was effective in treating a patient with dermatomyositis and hair loss.
research Gut microbes and skin disease, gut-brain-skin axis: A review
Balancing gut microbes and managing stress can help improve skin conditions like eczema and acne.
research Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis
Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
research Phospholipase's role in maintaining and restoring skin and hair health
Phospholipases help maintain and restore skin and hair health, potentially leading to new treatments for related conditions.
research Montagna Symposium 2016—The Skin: Our Sensory Organ for Itch, Pain, Touch, and Pleasure
The symposium highlighted the skin's role in sensing itch, pain, touch, and pleasure, and discussed new research and techniques for understanding and treating these sensations.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research Basic research in biostimulation
Low-output laser irradiation can stimulate or inhibit biological processes depending on the dose.
research Regulatory T Cell Heterogeneity in the Steady State and Tumor
Regulatory T cells adapt to different environments to control inflammation and support tissue repair.
research Skin Organoids for Disease Modelling, Drug Screening and Regenerative Medicine: Recent Advances and Future Perspectives
Skin organoids are improving research but need better blood supply, nerve function, and immune system integration.
research Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia
Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.