18 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
13 citations
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January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
12 citations
,
May 2017 in “Pharmacology & therapeutics” Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
11 citations
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February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
7 citations
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June 2024 in “Communications Medicine” Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
7 citations
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June 2019 in “Cureus” Fractional lasers and microneedling, combined with topical agents, could potentially treat Alopecia Areata effectively, but more research is needed due to limited data.
4 citations
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November 2023 in “Frontiers in immunology” New treatments targeting T-cell pathways are needed for better alopecia areata management.
1 citations
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March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
1 citations
,
January 2022 in “Research Square (Research Square)” CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” Targeting specific cell interactions may help treat skin fibrosis.
January 2025 in “RSC Pharmaceutics” Smart microneedles using advanced tech could improve psoriasis treatment.
October 2023 in “Frontiers in medicine” Targeted immunotherapy could be a promising new treatment for hair regrowth.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
November 2000 in “Current problems in dermatology” New treatments for hair loss and excessive hair growth show promise with few side effects and advancements in laser technology.
441 citations
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May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
66 citations
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
17 citations
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December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
8 citations
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October 2022 in “Cold Spring Harbor perspectives in biology” The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
1 citations
,
January 2016 in “Elsevier eBooks” The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
January 2026 in “Archives of Internal Medicine Research” PRP, exosomes, and physical therapies show promise for hair and tissue repair, but need more research for optimization.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
63 citations
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March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
38 citations
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September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
19 citations
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November 2023 in “npj Regenerative Medicine” Synthetic melanin applied to skin speeds up wound healing.
5 citations
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January 2018 The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
2 citations
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May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
48 citations
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January 2011 in “Hormone Research in Paediatrics” The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.