January 2025 in “Genetics in Medicine Open” A 33-year-old male initially misdiagnosed with neuromyelitis optica was found to have late onset biotinidase deficiency, a condition that can mimic neuromyelitis optica and multiple sclerosis. His symptoms included progressive spastic diplegia, bilateral optic atrophy, and peripheral neuropathy. Serum biotinidase testing revealed a marked deficiency, leading to a revised diagnosis. Treatment with 10 mg of biotin daily is underway, with potential for reversing ophthalmologic findings and some myelopathy. The case highlights the importance of considering biotinidase deficiency in similar clinical presentations, as testing is quick and inexpensive, and can significantly alter management. Further research is needed to understand the incidence of this deficiency in patients with neuromyelitis optica and multiple sclerosis diagnoses.
5 citations
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October 2021 in “Journal of the American Academy of Dermatology” PRAME helps distinguish between benign and malignant skin cells in most cases.
3 citations
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May 2018 in “Journal of Cosmetic Dermatology” Biopsy can differentiate between alopecia areata and androgenic alopecia, and if more information is needed, testing for CD3 and CD8 can help.
71 citations
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March 1995 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections for alopecia biopsies improves diagnosis without extra cost.
6 citations
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November 2018 in “American journal of transplantation” UV light helped human hair transplants survive in mice without broad immunosuppression.
7 citations
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February 2010 in “British Journal of Dermatology” A woman with a rare autoimmune disorder had a blister on her eye and unique immune reaction, which was effectively treated with medication.
July 2024 in “Journal of Investigative Dermatology” Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.
27 citations
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April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
68 citations
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
September 2020 in “Research Square (Research Square)” Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.
1 citations
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November 2023 in “Journal of neurology” A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.
32 citations
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August 2016 in “Science Signaling” Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.
April 2023 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
1 citations
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October 2023 in “PROTOPLASMA” 70 citations
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February 2018 in “Seminars in Arthritis and Rheumatism” Belimumab reduces disease activity, steroid use, and flares in lupus patients.
6 citations
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November 1977 in “International Journal of Legal Medicine” Human hair contains a substance that shows blood group A activity.
9 citations
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April 2024 in “Advanced Drug Delivery Reviews” 
January 2026 in “Inflammation and Regeneration” Two-photon microscopy improves skin imaging but faces safety and cost challenges for clinical use.
March 2023 in “Indian Journal of Rheumatology” Testing for various autoantibodies in Indian children with lupus can help predict disease symptoms and risks.
November 2024 in “Journal of Investigative Dermatology” Bimekizumab quickly improves psoriasis symptoms and skin at the molecular level.
January 2010 in “The Year book of perinatal/neonatal medicine” Early skin biopsy helps diagnose and manage severe skin conditions in babies.
10 citations
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May 2010 in “Analytica Chimica Acta” New tests detect finasteride and dutasteride in urine quickly and easily.
April 2018 in “Journal of Investigative Dermatology” Hydroxychloroquine may cause false results in tuberculosis tests for patients with autoimmune skin diseases.
November 2024 in “Journal of Investigative Dermatology” Dermal IgA deposition without symptoms is rare in Dermatitis herpetiformis risk groups.
28 citations
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January 2005 in “PubMed” Topical immunomodulators are effective and safe for treating immune-related skin conditions.
3 citations
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October 2024 in “Cancers” Skin side effects from melanoma immunotherapy are common and may indicate better survival.
A new compound from Royoporus badius activates immune cells and induces inflammatory responses.
14 citations
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September 2020 in “Journal of the American Academy of Dermatology” Electrical impedance spectroscopy improves biopsy accuracy and efficiency for skin lesions.
April 2020 in “International Journal of Dermatology” T-cell patterns in skin help distinguish alopecia areata from androgenetic alopecia.
5 citations
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April 2019 in “Phytochemical Analysis” The new ELISA method is reliable and eco-friendly for checking the quality of Pueraria candollei.