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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Immune system changes may contribute to female pattern hair loss.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

People on immune-modifying skin disease treatments may have a weaker antibody response to COVID-19 vaccines but often improve after the second dose.

Activated protein C helps protect mice from long-term radiation damage.

A new gene mutation causes insulin resistance in a girl and her mother.

Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.

Early over-expression of FoxN1 harms immune and skin development.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.

Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.

JAK inhibitors are effective for treating moderate-to-severe alopecia areata.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

DAVID syndrome is a condition with immune system and hormone deficiencies, needing early diagnosis to avoid serious complications.

Polyomavirus A2 infection in newborn mice caused hair follicle tumors.

A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.

MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.

Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Cell-based therapy using specific immune cells may help treat alopecia areata by promoting hair regrowth.

The gut microbiome affects the development of alopecia areata.

Understanding skin patterns can help us learn about skin diseases and their treatments.

Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.