research Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery
PLGA-based microneedles are promising for safe and effective skin delivery of drugs and vaccines.
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research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Zinc as an ambivalent but potent modulator of murine hair growth in vivo- preliminary observations
Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.
research Unmet Medical Needs in Chronic, Non-communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Engineering Pro‐Regenerative Hydrogels for Scarless Wound Healing
Hydrogels could lead to better treatments for wound healing without scars.
research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin
Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
research Current and Potential Agents for the Treatment of Alopecia Areata>
Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
research Adult skin acute stress responses to short‐term environmental and internal aggression from exposome factors
Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases?
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Chemotherapy of psoriasis and other skin disorders with oral retinoids
Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
research A novel therapeutic paradigm for patients with extensive alopecia areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Sarcoptic mange outbreak decimates South American wild camelid populations in San Guillermo National Park, Argentina
Sarcoptic mange nearly wiped out vicuñas and guanacos in an Argentine park.
research Natural pathogens of laboratory animals and their effects on research
Fungal infections in lab animals can interfere with research.
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Group IID, IIE, IIF and III secreted phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Aromatic plants as cosmeceuticals: benefits and applications for skin health
Aromatic plants can naturally help prevent skin aging and improve skin health.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Modified stem cells from umbilical cord blood can make hair grow faster.
research Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies
Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.
research Zinc: A complementary factor in the treatment of chronic hepatitis C? (Review)
Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.
research The use of mesenchymal stromal cells in the treatment of coronavirus disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
COVID-19 may harm male fertility and damage the reproductive system.
research The role of leptin in selected skin diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
research Skin diseases in consequence of endocrine alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research Incidental benefits after fecal microbiota transplant for ulcerative colitis
FMT for ulcerative colitis may also help with weight loss, hair loss, arthritis, and allergies.
research Intermittent and Persistent Type 2 lupus: patient perspectives on two distinct patterns of Type 2 SLE symptoms
SLE patients experience two patterns of non-inflammatory symptoms: intermittent and persistent.
research Unsuccessful Treatment of Alopecia Areata with Simvastatin/Ezetimibe: Experience in 12 Patients
Simvastatin/ezetimibe did not effectively treat severe alopecia areata and caused side effects in some patients.
research Progress and prospects: gene therapy for performance and appearance enhancement
Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.