102 citations
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April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
81 citations
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March 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered scaffolds help heal skin wounds, but perfect treatments are still needed.
75 citations
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November 2016 in “Medicines” Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
73 citations
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December 2010 in “Current opinion in infectious diseases/Current opinion in infectious diseases, with evaluated MEDLINE” Hidradenitis suppurativa is a skin condition possibly caused by hair follicle issues, with treatments focusing on infection and inflammation.
64 citations
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July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
63 citations
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April 1985 in “Journal of the American Academy of Dermatology” Topical PUVA can cause temporary hair regrowth in some alopecia areata patients but doesn't change the long-term outcome.
62 citations
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April 2002 in “Journal of the American Academy of Dermatology” Sulfasalazine may help regrow hair in severe alopecia areata cases.
60 citations
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September 2004 in “Pediatric Dermatology” A girl developed vitiligo and psoriasis after hepatitis B treatment, and stopping the treatment didn't help.
51 citations
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September 2015 in “Medical Clinics of North America” The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
48 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Contact sensitizers like DCP and SADBE are the most effective treatments for alopecia areata.
44 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” MSC-derived exosomes may help in skin repair and regeneration.
41 citations
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February 2001 in “Current pharmaceutical design” Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
38 citations
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January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
36 citations
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August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
32 citations
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February 2020 in “PTR. Phytotherapy research/Phytotherapy research” Rosemary extract may boost the immune system, but more research on humans is needed to confirm this.
31 citations
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December 2016 in “Anais Brasileiros de Dermatologia” DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.
31 citations
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January 1987 in “Dermatology” Minoxidil helps hair regrowth in severe alopecia areata by changing immune cell behavior.
30 citations
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March 2007 in “Expert opinion on drug safety” Cetuximab often causes skin rashes, and managing these is important for cancer treatment.
27 citations
,
July 2013 in “Journal of dermatological treatment” Laser therapy may effectively treat persistent scalp inflammation.
27 citations
,
May 2007 in “Archives of dermatological research” Diphencyprone treatment increases CD8 lymphocytes in the scalp, which is associated with hair regrowth in alopecia areata patients.
25 citations
,
March 2012 in “Journal of oncology pharmacy practice” An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
23 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
18 citations
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October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
16 citations
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December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
16 citations
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May 2006 in “PubMed” Alpha-melanocyte-stimulating hormone helps manage skin inflammation and protect against UV damage.
16 citations
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August 2003 in “Journal of The American Academy of Dermatology” Nitrogen mustard was not very effective for hair regrowth in alopecia areata and has potential skin cancer risk.
15 citations
,
May 2021 in “British journal of dermatology/British journal of dermatology, Supplement” Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
15 citations
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February 2021 in “Frontiers in immunology” Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
13 citations
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March 2020 in “Acta veterinaria Scandinavica” Stem cells from fat improve dog wound healing better than standard treatment.
11 citations
,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.