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UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Psoriasis patients on biologic therapy have a weaker immune response to COVID-19 vaccination than healthy people.

γδTregs may help treat autoimmune diseases like alopecia areata by promoting hair regrowth and reducing immune attacks.

Engineered exosomes show promise for improving wound healing but face challenges in clinical use.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

Skin cell-derived vesicles can help heal skin injuries effectively.

Oxidized LDL reduces cell growth but affects stem cell differentiation less negatively than cytokine-induced inflammation.

Certain Chinese herbs may help treat kidney fibrosis by targeting TGF-β.

Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Blocking EGFR can cause skin inflammation by disrupting IL-1 signaling.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

γδ T cells can prevent and treat alopecia areata, offering a new therapy option.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Increased Treg cells and IL-10 may help quick recovery in acute diffuse and total alopecia.

Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Advances in mechanobiology and immunology could lead to scarless wound healing.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

RNase L suppresses regeneration in mammals.

Targeting SOX proteins may improve cancer treatment by restoring immune function.

Pimecrolimus reduces the effectiveness of stem cell therapy for atopic dermatitis.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

New therapies like JAK inhibitors and stem cells show promise in treating vitiligo.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

γδT cells can protect hair follicles from alopecia areata and promote hair regrowth.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.