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research Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development

23 citations , April 2010 in “Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology”

The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.

research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

32 citations , November 2020 in “UNC Libraries”

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

research Effects of Gonadal Steroids on Melanocytes in Developing Hamsters

15 citations , June 1986 in “Pediatric Dermatology”

Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.

research [The establishment of hypospadias rat model and embryoteratogenic test of Atrazine].

9 citations , July 2007 in “PubMed”

Atrazine causes birth defects in rats, and finasteride can reliably create a hypospadias model.

research 1407 ANDROGENETIC ALOPECIA, PROSTATE VOLUME AND URINARY SYMPTOMS. IS THERE A RELATIONSHIP? A CASE-CONTROL STUDY

March 2010 in “The Journal of Urology”

Hair loss, prostate size, and urinary issues are related due to androgen effects.

Neonatal Inhibition of Androgen Activity Alters the Programming of Body Weight and Orexinergic Peptides Differentially in Male and Female Rats

research NEONATAL INHIBITION OF ANDROGEN ACTIVITY ALTERS THE PROGRAMMING OF BODY WEIGHT AND OREXINERGIC PEPTIDES DIFFERENTIALLY IN MALE AND FEMALE RATS

February 2024 in “Brain research bulletin”

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

research Effect of perfluorooctanesulfonate exposure on steroid hormone levels and steroidogenic enzyme activities in juvenile Silurana tropicalis

4 citations , March 2019 in “JAT. Journal of applied toxicology/Journal of applied toxicology”

PFOS exposure disrupts hormone levels and enzyme activities in juvenile frogs, affecting males and females differently.

research The postnatal offspring of finasteride-treated male rats show altered ERα and PCNA expression in the liver

July 2025 in “Reproductive Biology”

Finasteride use in male rats may harm their male offspring's liver function.

research The Effects of Perinatal Androgen Deprivation on Body Weight and Spatial Working Memory in Male Rats

April 2015 in “The FASEB Journal”

Blocking male hormones in baby rats improved memory and increased weight.

research Early lead exposure and pubertal development in a Mexico City population

29 citations , February 2019 in “Environment international”

Higher early lead exposure is linked to delayed puberty in girls.

Neonatal Finasteride Administration Alters Hippocampal α4 and δ GABAAR Subunits Expression and Behavioral Responses to Progesterone in Adult Rats

research Neonatal finasteride administration alters hippocampal α4 and δ GABAAR subunits expression and behavioural responses to progesterone in adult rats

17 citations , September 2013 in “The International Journal of Neuropsychopharmacology”

research Absence of Prostatic Growth in Large Cohort of Adult Female Patients with Congenital Adrenal Hyperplasia

7 citations , August 2012 in “The Journal of Urology”

Women with congenital adrenal hyperplasia showed no prostatic growth.

research The prevalence of androgen excess among patients with minimal unwanted hair growth

83 citations , December 2004 in “American Journal of Obstetrics and Gynecology”

research Sex-Chromosome-Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells

December 2023 in “International journal of molecular sciences”

Chromosomal differences affect how muscle cells respond to testosterone.

research El nuevo director de tecnología

January 2004 in “Banca y finanzas: Revista profesional de gestión financiera”

Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.

research Androgen Receptor Actions Modify Skin Structure and Chemical Carcinogen-induced Skin Cancer Susceptibility in Mice

14 citations , January 2015 in “Hormones and Cancer”

Androgen receptor inactivation delays skin cancer onset and reduces incidence in mice, with gender differences in susceptibility.

research Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride

8 citations , February 2014 in “General and Comparative Endocrinology”

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat

5 citations , December 2018 in “Frontiers in Endocrinology”

Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.

research Androgens and ovarian function: translation from basic discovery research to clinical impact

55 citations , May 2019 in “Journal of Endocrinology”

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

research The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency.

54 citations , November 1995 in “The Journal of Clinical Endocrinology & Metabolism”

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome

research In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome

September 2008 in “Fertility and Sterility”

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

research Morphological Features of External Genitalia in Hypospadiac Rat Model: 3-Dimensional Analysis

18 citations , March 2004 in “The Journal of Urology”

Hypospadiac rats showed abnormal genital development, useful for studying human hypospadias.

research Ectopic Adrenal Rests in Congenital Adrenal Hyperplasia as a Cause of Androgen Excess after Adrenalectomy Detected by Pelvic Venous Sampling

7 citations , January 2013 in “Hormone Research in Paediatrics”

Ectopic adrenal rests can cause androgen excess after adrenalectomy and may need targeted surgery.

research Expression Profiles of Reproduction- and Thyroid Hormone-Related Transcripts in the Brains of Chemically-Induced Intersex Frogs

24 citations , January 2011 in “Sexual Development”

Intersex frogs have different brain gene activity related to sex and thyroid hormones.

research Hormonal status of male reproductive system: androgens and estrogens in the testis and epididymis. In vivo and in vitro approaches.

43 citations , January 2006 in “PubMed”

Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.

research Modificazioni nella funzionalità , nell'espressione dei recettori GABAA extrasinaptici e nella plasticità sinaptica nell'ippocampo di ratto durante la gravidanza e dopo il parto.

January 2009

During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.

research LACK OF EFFECT OF OESTROGENS ON ADRENAL ANDROGEN SECRETION IN CHILDREN AND ADOLESCENTS WITH A COMMENT ON OESTROGENS AND PUBIC HAIR GROWTH

26 citations , March 1981 in “Clinical Endocrinology”

Oestrogen does not affect adrenal androgen levels in children and adolescents.

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