26 citations
,
January 2019 in “Experimental Dermatology” Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
30 citations
,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
101 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
91 citations
,
March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
68 citations
,
February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Keratin films from human hair can potentially replace human nail plates for drug testing.
24 citations
,
October 2022 in “Cell Regeneration” A new mouse model effectively mimics vitiligo for research and drug testing.
20 citations
,
October 2018 in “Physics and chemistry of liquids” Minoxidil dissolves better in ethanol-water mixtures at different temperatures, with water playing a key role.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
8 citations
,
May 2024 in “PLoS Biology” Gap junctions help control feather pattern formation in chickens.
8 citations
,
January 2013 in “The scientific world journal/TheScientificWorldjournal” Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
3 citations
,
March 2023 in “Scientific Reports” Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
1 citations
,
February 2021 in “Journal of Natural Remedies” Ficus religiosa and Morus alba extracts improved hair growth and follicle regeneration in mice.
April 2026 in “Journal of Dermatological Science” Hair organoids are effective for testing hair loss treatments.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
April 2023 in “Journal of Investigative Dermatology” Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
September 2015 in “Fluids and Barriers of the CNS” Three skull models were found most useful for testing hydrocephalus valve programming.
35 citations
,
January 1990 in “PubMed” Cyclosporin A boosts hair growth in nude mice, but minoxidil does not.
35 citations
,
October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
17 citations
,
May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
11 citations
,
March 2020 in “Cellular Signalling” XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
7 citations
,
December 2015 in “Experimental Dermatology” Sh-Polypeptide 9 may be better than minoxidil for hair growth and protection against damage.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
March 2023 in “Research journal of pharmacy and technology” The herbal hair oil helped hair grow in mice.
January 2013 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” Hydrophobized silica nanoparticles penetrate the skin's outer layer more effectively, while hair follicle density doesn't impact their accumulation.
90 citations
,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
28 citations
,
March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
26 citations
,
October 2020 in “Biomedicines” Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
November 2025 in “Scientific Reports” COVID-19 may cause hair loss by affecting hair follicles.
October 2025 in “Records of Natural Products” Kaempferol promotes hair growth and could be a natural treatment for hair loss.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.