20 citations
,
September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
November 2025 in “Drug Testing and Analysis” Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.
In vitro methods are crucial for developing effective and humane cosmetic ingredients.
43 citations
,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
12 citations
,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
9 citations
,
January 2006 in “Cutaneous and ocular toxicology” L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
48 citations
,
April 2021 in “Pharmaceuticals” Liposomal curcumin improves skin cancer treatment effectiveness while sparing normal cells.
April 2023 in “Journal of Investigative Dermatology” The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
April 2025 in “Pharmaceuticals” APA is a promising new compound for repairing damaged hair, outperforming Olaplex® in strength and elasticity.
January 2007 in “The FASEB journal” Human hair keratins help nerve regeneration and support Schwann cell activity.
5 citations
,
November 2024 in “Cells” Fish cell spheroids are a promising tool for replicating real-life conditions in research.
1 citations
,
August 2025 in “Frontiers in Bioengineering and Biotechnology” A 3D skin model helps study wound healing better than traditional methods.
32 citations
,
August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
169 citations
,
January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
13 citations
,
August 2007 in “Journal of Investigative Dermatology” Mouse hair can regrow in a special lab setup without serum.
5 citations
,
October 2022 in “Heliyon” Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.
5 citations
,
October 2020 in “Bioengineering & translational medicine” Researchers used a laser to create advanced skin models with hair-like structures.
November 2022 in “Journal of Investigative Dermatology” 3D skin bioprinting, using skin bioinks like collagen and gelatin, is growing fast and could help treat wounds, burns, and skin cancers, as well as test cosmetics and drugs.
3 citations
,
January 1991 in “Toxicology in Vitro” Hair follicle cultures are effective for studying cell communication and testing chemicals.
27 citations
,
June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
April 2026 in “Journal of Dermatological Science” Hair organoids are effective for testing hair loss treatments.
18 citations
,
June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
6 citations
,
February 2024 in “Pharmaceutics” ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.
February 2024 in “Research Square (Research Square)” Strat-M® membrane can effectively replace mouse skin for testing collagen peptide delivery.
45 citations
,
January 2022 in “Lab on a Chip” The platform effectively grows lung cancer cell spheroids for drug testing.
21 citations
,
April 2021 in “Biofabrication” The study created a skin model with realistic blood vessels that improves skin grafts and testing for drug delivery.
20 citations
,
May 2011 in “Journal of Clinical Investigation” The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.
June 1967 in “Journal of Cellular Physiology” The 3D hair follicle model improves understanding of hair growth and drug testing.