research 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA)
ILC1 cells contribute to hair loss in alopecia areata.
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research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Low Humidity Alters Epidermal Gene Expression in vivo
Low humidity changes skin gene expression, but emollients can help manage these changes.
research Hallmark evidence of lipopolysaccharide (LPS) tolerance in obese women with polycystic ovary syndrome (PCOS) - LPS-induced NFkB suppression in mononuclear cells (MNC) is linked to hyperandrogenism in PCOS
High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
research Immunosenescence and inflammaging in Parkinson’s disease: mechanisms and therapeutic prospects
Age-related immune changes worsen Parkinson's disease, suggesting new treatment strategies.
research Topical Metformin In Dermatology: A Narrative Review Of Efficacy And Formulation Approaches
Topical metformin shows promise for treating skin conditions like acne and psoriasis.
research Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons
Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
research Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
research Embryonic-like regenerative phenomenon: wound-induced hair follicle neogenesis
New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice
Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
research The role of multiomics in revealing the mechanism of skin repair and regeneration
Multiomics helps understand and improve skin healing and repair.
research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
Blocking certain receptors in the lungs might help treat a specific type of asthma.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research What “regenerative” means in aesthetic medicine: a narrative literature review attempting to demystify the core essence of regenerative aesthetics
Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
research A proteoglycan-based topical treatment for hair greying: in vitro antioxidant and pro-melanogenic effects
PP-PTKL may help treat hair greying, but more testing is needed.
research Sanhuang Fukang oil alleviates X-ray-induced skin injury by reducing inflammation and apoptosis: an in vivo study
Sanhuang Fukang oil helps heal radiation skin injuries by reducing inflammation and cell death.
research DNA Methylation‐Regulated ZDHHC17 Promotes the Risk of Facial Skin Aging
ZDHHC17 methylation may help treat or identify facial skin aging.
research Malassezia and the Asian menopausal skin
Menopause-related skin changes may increase fungal infections and inflammation.
research Genome-Wide Association Studies for Immunoglobulin Concentrations in Colostrum and Serum in Chinese Holstein
Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning
Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
research Quoi de neuf en recherche dermatologique ?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes
Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.