701 citations
,
August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
245 citations
,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
72 citations
,
January 2012 in “Annals of Dermatology” IGF-I promotes hair growth by keeping hair follicles in the growth phase longer.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.
51 citations
,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
43 citations
,
September 2021 in “Nutrients” Persimmons offer health benefits and can be used in new products and sustainable applications.
39 citations
,
April 2023 in “Science Advances” CD34+ cells help heal damaged limbs by promoting blood vessel growth.
37 citations
,
August 2020 in “BMC Genomics” Hair greying is mainly influenced by age, with genetics playing a smaller role.
32 citations
,
February 2024 in “The Journal of Experimental Medicine” CXCL12+ fibroblasts help recruit neutrophils to fight skin infections.
29 citations
,
April 2019 in “Acta neuropathologica communications” Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
29 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
25 citations
,
February 2021 in “Diabetes” Dock5 is important for skin healing and could help treat diabetic wounds.
20 citations
,
December 2019 in “International Journal of Molecular Sciences” HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.
20 citations
,
February 2018 in “Cell transplantation” Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.
18 citations
,
July 2023 in “International Journal of Molecular Sciences” KY19382 speeds up wound healing by activating a specific cell signaling pathway.
17 citations
,
September 2024 in “Cosmetics” Cold-pressed plant oils have valuable natural antioxidants and skin care benefits.
16 citations
,
January 2023 in “Gynecological Endocrinology” Liver damage in PCOS is linked to iron overload and cell death due to the miR-761-hepcidin/GPX4 pathway.
12 citations
,
April 2019 in “Scientific Reports” A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
11 citations
,
March 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
10 citations
,
May 2020 in “International Journal of Molecular Sciences” Hair follicles can be used to study gene mutations in Stargardt disease.
9 citations
,
August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
9 citations
,
March 2022 in “Military Medical Research” Small molecules can help turn skin cells into sweat gland-like cells for potential skin repair.
8 citations
,
January 2022 in “BMC Biology” Environmental factors affect reproductive traits by altering the SRD5A1 gene.
7 citations
,
May 2025 in “Journal of Biomedical Science” Keratin 6A increases skin inflammation, suggesting it could be a target for treating certain skin diseases.
7 citations
,
March 2022 in “International Journal of Molecular Sciences” FGF21 can help reduce skin inflammation caused by C. acnes.
6 citations
,
May 2023 in “Molecules” Cepharanthine dry powder inhalers may effectively treat acute lung injury by reducing inflammation.
4 citations
,
February 2025 in “Pharmaceuticals” Voglibose may help treat skin hyperpigmentation safely.
4 citations
,
October 2024 in “International Journal of Molecular Sciences” Naringin may help treat atopic dermatitis by reducing inflammation and improving the skin barrier.
4 citations
,
July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
4 citations
,
November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.