research Crystal Structure and Synthesis of 17.ALPHA.-Acetoxy-6,7-epoxypregn-4-ene-3,20-dione
A new compound was made that might help treat diseases related to male hormones.
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research 1103 Derinat extends hair cycle at anagen phase by decreasing the level of TRPCs-mediated intracellular ROS accumulation in skin
Derinat helps extend hair growth by reducing harmful molecules in skin cells.
research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols
Synthetic biology can improve sesquiterpenol production by using innovative microbial strategies.
research Pharmacological Activity of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research Topical Carrier-Free Delivery of Finasteride and Peptides for Enhanced Hair Growth
A new topical method using peptides boosts hair growth effectively with less finasteride and fewer side effects.
research Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Phytochemicals and Pharmacological Properties of Nyctanthes arbor-tristis: A Review
Nyctanthes arbor-tristis is effective for treating many health issues.
research Exploring murE protein inhibitors of Tropheryma whipplei through pharmacoinformatic approaches incorporating solubility-enhancing formulation insights
[6]-Gingerdiol 3-monoacetate shows promise for treating T. whipplei infections.
research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs
Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
research Nanoemulgel as an innovative platform for phytomolecules
Nanoemulgel improves delivery and effectiveness of plant-based drugs for various conditions.
research Production of biologically active oxidized derivatives of finasteride through metabolism byAspergillus nigerculture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
research Therapeutic Effects of Natural Products on Human Diseases
Natural products can safely and effectively treat various human diseases.
research Cortexolone 17a-propionate: A new antiandrogen acting on hair dermal papilla cells for the treatment of androgenic alopecia
Cortexolone 17a-propionate may be an effective new treatment for hair loss.
research In Vitro Skin Penetration of 5α-Reductase Inhibitors from Tectona grandis L.f. Leaf Extracts
Tectona grandis leaf extracts, especially with propylene glycol, may be promising for topical hair loss treatments.
research Phytochemical composition, antibacterial and antioxidant activities of the ethanolic root extract of the endemic Onosma, northern Iran.
The ethanolic root extract of Onosma dichroantha has strong antioxidant and antibacterial properties.
research Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase
Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
research Success and Controversy of Natural Products as Therapeutic Modulators of Wnt Signaling and Its Interplay with Oxidative Stress: Comprehensive Review Across Compound Classes and Experimental Systems
Natural products show promise for treating diseases but need more research to understand and use them effectively.
research ANDROGRAPHOLIDE LOADED TOPICAL NANOCARRIERS FOR MANAGEMENT OF PSORIASIS: A SAFE AND EFFECTIVE APPROACH
Andrographolide-loaded topical nanocarriers are a safe and effective treatment for psoriasis.
research Disease modifying osteoarthritis drug discovery using a temporal phenotypic reporter in 3D aggregates of primary human chondrocytes
Aromoline and DRD4 are potential targets for osteoarthritis treatment.
research A review of the botany, ethnopharmacology, phytochemistry, pharmacology, toxicology and quality of Anemarrhena asphodeloides Bunge
The plant Anemarrhena asphodeloides has multiple health benefits but its safety at certain doses is uncertain.
research Enhanced hair follicle accumulation and androgenetic alopecia treatment of finasteride by topical nanoparticles hydrogel system
A new topical finasteride gel using nanoparticles shows promise for safe and effective hair regrowth.
research Breaking the “rule-of-five” to access Bridged Bicyclic Heteroaromatic Bioisosteres
A new method creates valuable compounds for drug discovery by breaking traditional chemical rules.
research Ethnobotany, Pharmacology and Major Bioactive Metabolites from Impatiens Genus Plants and their Related Applications
Impatiens plants have potential health benefits but need more research.
research Antibacterial Activity Test of NADES (Natural Deep Eutectic Solvents) Extract of Mangkokan Leaves (Polyscias Scutellaria) Against Escherichia Coli and Staphylococcus Aureus Bacteria
Mangkokan leaf extract can fight bacteria and may help prevent hair loss and treat infections.
research <p>Study of the interaction between self-assembling peptide and mangiferin and in vitro release of mangiferin from in situ hydrogel</p>
RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
research Chemical profiles and pharmacological attributes of Apis cerana indica beehives using combined experimental and computer-aided studies
Beehive extracts may help with anxiety, depression, and inflammation.
research Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation
Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
research Hair Growth Promoting Effect of Dicerocaryum senecioides Phytochemicals
Chemicals from the plant Dicerocaryum senecioides were found to safely speed up and increase hair growth in mice.
research Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay
A new plant extract from Avicennia marina could potentially be used to treat common hair loss.