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Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

In 2017, Spanish dermatologists most often prescribed minoxidil and finasteride for male hair loss, and minoxidil and oral contraceptives for premenopausal female hair loss.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Alstonia boonei phytochemicals show promise as alternative treatments for BPH with fewer side effects than current drugs.