September 2025 in “Wound Repair and Regeneration” Understanding how new hair follicles form after skin injury could help prevent scars.
46 citations
,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
24 citations
,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
252 citations
,
April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
10 citations
,
December 2015 in “International Journal of Molecular Sciences” PDCD4 is important for controlling skin cell growth and healing.
6 citations
,
June 2012 in “Physiology” The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.
33 citations
,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
168 citations
,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
162 citations
,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
135 citations
,
December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
81 citations
,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
46 citations
,
May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
11 citations
,
November 2005 in “The Journal of Dermatology” A man's crushed thumb caused unusual horizontal nail ridges on all fingers of one hand.
4 citations
,
January 2025 in “Frontiers in Pharmacology” Multiomics helps understand and improve skin healing and repair.
July 2021 in “Indian Journal of Animal Research” Using platelet-rich plasma with primary repair improves healing in penile fractures.
48 citations
,
March 2019 in “Frontiers in Physiology” Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
354 citations
,
February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
265 citations
,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
69 citations
,
September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.
47 citations
,
March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
41 citations
,
September 2005 in “Wound Repair and Regeneration” Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.
19 citations
,
August 2008 in “Journal of The European Academy of Dermatology and Venereology” Bald areas have lower cell growth, more DNA damage, and increased cell death.
16 citations
,
March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
13 citations
,
September 2002 in “Dermatologic Surgery” Effective repair of bad hair transplants requires skilled techniques and careful use of donor hair, with strategies like reimplantation and camouflage, and new methods to minimize scarring.
10 citations
,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
9 citations
,
January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
9 citations
,
November 2008 in “Facial Plastic Surgery” Effective scalp reconstruction requires a wide range of surgical skills and an understanding of hair biology.
1 citations
,
December 2023 in “npj biofilms and microbiomes” Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.
1 citations
,
May 2021 in “Research Square (Research Square)” Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.