research Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes
Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
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480-510 / 1000+ resultsresearch Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair
Melatonin protects the skin by scavenging free radicals and repairing DNA damage.
research Normal stem cells and cancer stem cells: similar and different
Deregulation of stem cell function is central to the development of some cancers.
research The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development
Fgfr2b helps maintain healthy skin and prevent cancer.
research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Characterization and Localization of Side Population Cells in Mouse Skin
Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
research Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles
Stem cells in developing hair follicles move to specific areas as they mature.
research Keratins and skin disease
Keratin mutations cause skin diseases and could lead to new treatments.
research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure
Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein
MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
research Alopecia areata and the gut—the link opens up for novel therapeutic interventions
Gut health may influence Alopecia Areata, suggesting new treatments.
research <p>The regenerative potential of skin and the immune system</p>
The skin's immune system helps it regenerate and fight infections.
research Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production
Lack of a key enzyme causes severe skin issues and death in mice.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?
TGase 3 helps build hair structure by forming strong bonds between proteins.
research The effect of various cosmetic pretreatments on protecting hair from thermal damage by hot flat ironing.
Polymeric pretreatments can significantly reduce hair breakage and damage from hot flat irons.
research Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles
The upper hair follicle is stable, while the lower part allows movement during hair growth.
research Effects of chemical structures of polycarboxylic acids on molecular and performance manipulation of hair keratin
A non-toxic formula using polycarboxylic acids strengthens and improves hair.
research Bulge cells of human hair follicles: segregation, cultivation and properties
Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
research Cuticle damage and the tensile properties of human hair
Cuticle damage doesn't affect hair's tensile strength; the cortex is responsible for it.
research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin
sPLA2-IIE is crucial for normal hair follicle structure and skin health.
research Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells.
Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
research The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations
Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
research Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1
Hair follicle stem cells can become corneal-like cells with the help of pax6.
research ADSCs inhibit photoaging‐ and photocarcinogenesis‐related inflammatory responses and extracellular matrix degradation
ADSCs help protect skin from UV damage and aging.
research Expansion of the spectrum of ITGB6-related disorders to adolescent alopecia, dentogingival abnormalities and intellectual disability
A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
ABCG2 protein marks stem-like skin cells in human epidermis.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research Curly hair: measured differences and contributions to breakage
Curly hair breaks more easily, especially with chemical treatments, but simpler grooming reduces breakage.