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research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin

124 citations , November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology”

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

research Localization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in Skin

119 citations , August 2010 in “Journal of Investigative Dermatology”

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

research The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth

109 citations , February 2018 in “CB/Current biology”

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

research Fluorescence Microscopy—An Outline of Hardware, Biological Handling, and Fluorophore Considerations

97 citations , December 2021 in “Cells”

Designing effective fluorescence microscopy experiments requires careful consideration of hardware, biological models, and imaging agents.

research K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) Represent the Type I Inner Root Sheath Keratins of the Human Hair Follicle

93 citations , July 2006 in “Journal of Investigative Dermatology”

K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.

research A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle

86 citations , May 2002 in “Journal of Investigative Dermatology”

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

85 citations , January 2018 in “Cell stem cell”

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

research Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease

85 citations , March 2008 in “Journal of Cell Science”

The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.

research Two Hydroxyproline Galactosyltransferases, GALT5 and GALT2, Function in Arabinogalactan-Protein Glycosylation, Growth and Development in Arabidopsis

63 citations , May 2015 in “PloS one”

GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.

research Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

61 citations , April 2023 in “Bioactive Materials”

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

research Fucoidan-derived carbon dots against Enterococcus faecalis biofilm and infected dentinal tubules for the treatment of persistent endodontic infections

61 citations , July 2022 in “Journal of Nanobiotechnology”

Fucoidan-derived carbon dots can effectively treat root canal infections by killing bacteria and are safer than traditional disinfectants.

research Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors

56 citations , February 2013 in “International Journal of Molecular Medicine”

Growth factors help hair follicle stem cells grow and stay versatile.

research Sostdc1 defines the size and number of skin appendage placodes

56 citations , February 2012 in “Developmental biology”

Sostdc1 controls the size and number of hair and mammary gland structures.

research Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation

56 citations , November 2003 in “Journal of Investigative Dermatology”

MMP-19 may worsen skin diseases by affecting skin growth and inflammation.

research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure

51 citations , January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.

research Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic

50 citations , December 2017 in “British Journal of Dermatology”

Different skin cells produce unique materials, which can improve skin substitutes for healing.

research Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA

49 citations , June 2019 in “eLife”

Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.

research
Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation

45 citations , March 2020 in “International Journal of Nanomedicine”

Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.

research Functional characterization of soybean strigolactone biosynthesis and signaling genes in Arabidopsis MAX mutants and GmMAX3 in soybean nodulation

43 citations , December 2017 in “BMC Plant Biology”

GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.

research An unexpected role for keratin 10 end domains in susceptibility to skin cancer

43 citations , October 2006 in “Journal of Cell Science”

Keratin 10 end domains may increase skin cancer risk by reducing cell death.

research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation

42 citations , December 2011 in “The journal of immunology/The Journal of immunology”

RANKL causes lymph nodes to grow by making certain cells multiply.

research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency

39 citations , November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

Fatp4 is crucial for healthy skin development and function.

research Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin

37 citations , May 2018 in “Frontiers in physiology”

Certain RNA molecules are important for the development of wool follicles in sheep.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

sPLA2-X is crucial for normal hair growth and follicle health.

research Heterogeneous nutrient supply promotes maize growth and phosphorus acquisition: additive and compensatory effects of lateral roots and root hairs

30 citations , July 2021 in “Annals of Botany”

Localized nutrients boost maize growth and phosphorus uptake by enhancing root hairs and lateral roots.

research The use of auto-antibody testing in the evaluation of interstitial lung disease (ILD) – A practical approach for the pulmonologist

26 citations , February 2016 in “Respiratory Medicine”

Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.

research Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation

25 citations , February 2025 in “Frontiers in Bioengineering and Biotechnology”

New skin repair methods show promise but need to be safer and more accessible.

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