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Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Organoid technology helps create mini-organs for studying diseases and testing drugs.

SOX9 is essential for the development of various organs and hair follicles.

Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Targeting colon cancer stem cells might lead to better treatment results.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

A patient with granuloma annulare experienced both isotopic and isomorphic responses, with skin lesions responding to steroids but relapsing after stopping treatment.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.

Ephrins slow down skin and hair follicle cell growth.

A special microbe helps plants absorb rock phosphate by growing on their root hairs.

The DiLiCre mouse model is an effective tool for precise genome editing using light.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.

Dyed chitin nanofibers are strong, colorful, and water-resistant, enhancing resin strength and color.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.